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Gene Expression Data
Assay Details
Assay
Reference: J:116645 Cota CD, et al., Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis. Dev Dyn. 2006 Dec;235(12):3438-47
Assay type: RNA in situ
MGI Accession ID: MGI:5553302
Gene symbol: Lefty1
Gene name: left right determination factor 1
Probe: Lefty probe
Probe preparation: Antisense
Assay notes: Probe used recognizes both family members.
Results
Specimen 5D: embryonic day 8.0-8.5 (more )
Structure Level Pattern Image Note
TS12: neural tube floor plate Present 5D

Specimen 5E/J: embryonic day 8.0-8.5; Mgrn1md-2J/Mgrn1md-2J (more )
Structure Level Pattern Image Note
TS12: neural tube floor plate Present 5E , 5J 76% mutants had normal expression.

Specimen 5F: embryonic day 8.0-8.5; Mgrn1md-2J/Mgrn1md-2J (more )
Structure Level Pattern Image Note
TS12: neural tube floor plate Absent 5F 24% mutants had no expression.

Specimen 5G: embryonic day 8.0-8.5; Mgrn1md-2J/Mgrn1md-2J (more )
Structure Level Pattern Image Note
TS12: neural tube floor plate Absent 5G 24% mutants had no expression.

Specimen 5H: embryonic day 8.0-8.5; Mgrn1md-2J/Mgrn1md-2J (more )
Structure Level Pattern Image Note
TS12: neural tube floor plate Absent 5H 24% mutants had no expression.

Specimen 5I: embryonic day 8.0-8.5; Mgrn1md-2J/Mgrn1md-2J (more )
Structure Level Pattern Image Note
TS12: neural tube floor plate Present 5I 76% mutants had normal expression.

Specimen 5K: embryonic day 8.0-8.5; Mgrn1md-2J/Mgrn1md-2J (more )
Structure Level Pattern Image Note
TS12: neural tube floor plate Present Regionally restricted 5K 76% mutants had normal expression. Expressed in the left side of the presumptive floor plate.

Specimen 5L: embryonic day 8.0; Mgrn1md-2J/Mgrn1md-2J (more )
Note: 2-3 somites
Structure Level Pattern Image Note
TS12: neural tube floor plate Present 5L 76% mutants had normal expression.

Specimen 5M: embryonic day 8.0; Mgrn1md-2J/Mgrn1md-2J (more )
Note: 2-3 somites
Structure Level Pattern Image Note
TS12: neural tube floor plate Present Regionally restricted 5M 76% mutants had normal expression. Expressed in the left side of the presumptive floor plate.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory