Gene Expression Data
Assay Details
Assay
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Reference:
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J:116645
Cota CD, et al., Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis. Dev Dyn. 2006 Dec;235(12):3438-47
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5553301
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Gene symbol:
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Nodal
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Gene name:
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nodal growth differentiation factor
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Results
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Specimen
5A:
embryonic day 8.0
(more )
Note: 5 somites
Specimen
5A:
(close )
Genetic Background:
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C3H/HeJ
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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5 somites
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Specimen
5B:
(close )
Genetic Background:
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involves: 129S1/SvImJ * C3H/HeJ
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Mutant Allele(s):
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Mgrn1md-2J/Mgrn1md-2J
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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3 somites
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Structure |
Level |
Pattern |
Image |
Note |
TS12: node |
Present |
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5B
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47 out of 48 examined mutants had this normal expression.
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TS12: lateral plate mesoderm |
Present |
Regionally restricted |
5B
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Asymmetrically expressed in the left lateral plate mesenchyme. 47 out of 48 examined mutants had this normal expression.
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Specimen
5C:
(close )
Genetic Background:
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involves: 129S1/SvImJ * C3H/HeJ
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Mutant Allele(s):
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Mgrn1md-2J/Mgrn1md-2J
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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6 somites
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Structure |
Level |
Pattern |
Image |
Note |
TS12: lateral plate mesoderm |
Present |
Regionally restricted |
5C
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One of 48 examined mutants showed reduced bilateral expression in the cardiac lateral plate mesoderm.
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TS12: node |
Absent |
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5C
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Just this one mutant.
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