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Gene Expression Data
Assay Details
Assay
Reference: J:116645 Cota CD, et al., Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis. Dev Dyn. 2006 Dec;235(12):3438-47
Assay type: RNA in situ
MGI Accession ID: MGI:5553301
Gene symbol: Nodal
Gene name: nodal growth differentiation factor
Probe: Nodal cDNA3
Probe preparation: Antisense
Results
Specimen 5A: embryonic day 8.0 (more )
Note: 5 somites
Structure Level Pattern Image Note
TS12: node Present 5A
TS12: lateral plate mesoderm Present Regionally restricted 5A Asymmetrically expressed in the left lateral plate mesenchyme.

Specimen 5B: embryonic day 8.0; Mgrn1md-2J/Mgrn1md-2J (more )
Note: 3 somites
Structure Level Pattern Image Note
TS12: node Present 5B 47 out of 48 examined mutants had this normal expression.
TS12: lateral plate mesoderm Present Regionally restricted 5B Asymmetrically expressed in the left lateral plate mesenchyme. 47 out of 48 examined mutants had this normal expression.

Specimen 5C: embryonic day 8.0; Mgrn1md-2J/Mgrn1md-2J (more )
Note: 6 somites
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present Regionally restricted 5C One of 48 examined mutants showed reduced bilateral expression in the cardiac lateral plate mesoderm.
TS12: node Absent 5C Just this one mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory