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Gene Expression Data
Assay Details
Assay
Reference: J:117237 Pennisi DJ, et al., Crim1(KST264/KST264) mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems. Dev Dyn. 2007 Feb;236(2):502-11
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5553115
Gene symbol: Crim1
Gene name: cysteine rich transmembrane BMP regulator 1
Reporter: lacZ
Direct Detection
Results
Specimen 2A: postnatal adult; Crim1Gt(KST264)Byg/Crim1+ (more )
Note: Hemi-mount.
Structure Level Pattern Image Note
TS28: renal vasculature Strong 2A Expression is in the kidney arterial plexus, absent in the venous plexus.
TS28: afferent arteriole of mature renal corpuscle Strong 2A
TS28: glomerular tuft Present 2A

Specimen 2B: postnatal adult; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS28: renal proximal tubule Present 2B
TS28: renal corpuscle Present Regionally restricted 2B Expression is in mesangial cells.
TS28: glomerular tuft Present Regionally restricted 2B Expression is in glomerular epithelial cells.

Specimen 2C: postnatal adult; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS28: glomerular tuft Present 2C
TS28: renal vasculature Present 2C Expression is in the vascular smooth muscle.

Specimen 2D: postnatal adult; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS28: renal distal tubule Present 2D

Specimen 2E: postnatal adult; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS28: renal distal tubule Present 2E

Specimen 2F: embryonic day 8.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS13: yolk sac Present Regionally restricted 2F Expression is in the blood islands.
TS13: trophectoderm Present Regionally restricted 2F Expression is around the ectoplacental cone.

Specimen 2G: embryonic day 10.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS17: branchial arch Present 2G
TS17: eye Present 2G
TS17: forebrain Present 2G
TS17: heart Present 2G
TS17: future spinal cord Present Regionally restricted 2G

Specimen 2H: embryonic day 12.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS20: eye Strong 2H
TS20: pinna Strong 2H
TS20: spinal cord Strong 2H
TS20: epidermis Strong Regionally restricted 2H Expression is in peridermal cells.

Specimen 2I: embryonic day 15.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS23: eye Strong 2I
TS23: limb Strong 2I
TS23: pinna cartilage condensation Strong 2I
TS23: spinal cord Strong 2I
TS23: vibrissa Strong 2I

Specimen 2J: embryonic day 10.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS17: dorsal aorta Present Regionally restricted 2J Expression is in the endothelium.
TS17: neural tube lateral wall Present Regionally restricted 2J Expression is in motor neurons.

Specimen 2K: embryonic day 10.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS17: heart Present Regionally restricted 2K Expression is in epicardial cells adjacent to the myocardium.
TS17: pericardial component Present 2K

Specimen 2L: embryonic day 12.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS20: forelimb digit Present 2L

Specimen 2M: embryonic day 15.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS23: forelimb Present 2M

Specimen 2N: embryonic day 16.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS24: forelimb mesenchyme Present Regionally restricted 2N Expression is in the cartilage condensations.
TS24: forelimb skin Present Regionally restricted 2N Expression is in the basal layer of the epidermis.

Specimen 2O: embryonic day 17.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS25: heart Present Regionally restricted 2O Expression is in the epicardium covering the ventricles and atria.
TS25: blood vessel Present Regionally restricted 2O Expression is in the adventitia of the outflow vessels.
TS25: coronary artery Present 2O

Specimen 2P: embryonic day 17.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS25: heart Present Regionally restricted 2P Expression is in the epicardium.

Specimen 2Q: embryonic day 17.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS25: coronary artery Present Regionally restricted 2Q Expression is in smooth muscle cells and the endothelium.
TS25: endocardial tissue Present 2Q

Specimen 2R: embryonic day 17.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS25: heart left ventricle Present Regionally restricted 2R Expression is in endocardial endothelial cells of a trabeculated portion of the left ventricle.

Specimen 2S: embryonic day 15.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS23: renal vasculature Present Regionally restricted 2S Expression is in vascular smooth muscle.
TS23: urothelium of ureter Present 2S
TS23: ureteral smooth muscle layer Weak 2S

Specimen 2T: embryonic day 15.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS23: renal tubule Present 2T
TS23: metanephros Present Regionally restricted 2T Expression is in mesangial cells.
TS23: maturing glomerular tuft Present Regionally restricted 2T Expression is in glomerular epithelial cells.
TS23: visceral epithelium of maturing renal corpuscle Weak 2T

Specimen 2U: embryonic day 15.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS23: adrenal gland Present 2U Including the suprarenal ganglion.

Specimen 2V: embryonic day 17.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS25: trophoblast giant cell Present 2V Expression is in giant trophoblast cells of the placenta.

Specimen 2W: embryonic day 17.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS25: lung epithelium Present 2W

Specimen 2X: embryonic day 17.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 2X Expression is in the basal layer of the epidermis.
TS25: hair follicle Present Regionally restricted 2X Expression is in the epithelium.

Specimen 2Y: postnatal adult; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS28: detrusor muscle of bladder Strong 2Y
TS28: lamina propria of bladder Present 2Y
TS28: urothelium of bladder Present 2Y

Specimen 2Z: postnatal adult; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS28: vasculature of bladder Present Regionally restricted 2Z Expression is in the vascular smooth muscle of arteries of the bladder.

Specimen 2AA: postnatal adult; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Cell Type Level Pattern Image Note
TS28: testis Present Regionally restricted 2AA Expression is in smooth muscle cells.
TS28: Leydig cell Leydig cell Present 2AA
TS28: Sertoli cell Sertoli cell Present 2AA

Specimen 2BB: embryonic day 17.5; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS25: ovary Present Regionally restricted 2BB Expression is in granulosa cells of an ovarian follicle and is strong in the ovarian surface epitelium.

Specimen 2CC: postnatal adult; Crim1Gt(KST264)Byg/Crim1+ (more )
Structure Level Pattern Image Note
TS28: ovary follicle Present Regionally restricted 2CC Expression is in the atresing follicle.
TS28: corpus luteum Present 2CC
TS28: surface epithelium of ovary Present 2CC

Specimen 3C: embryonic day 12.5; Crim1Gt(KST264)Byg/Crim1Gt(KST264)Byg (more )
Structure Level Pattern Image Note
TS20: embryo Present 3C There is blebbing of the skin in this mutant.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory