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Gene Expression Data
Assay Details
Assay
Reference: J:111612 Uemura M, et al., alphaN-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Dev Dyn. 2006 May 11;235(9):2559-2566
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5547983
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody
Results
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cranial nerve Present 2A
TS19: peripheral nervous system Present 2A
Specimen 2B: embryonic day 11.5; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS19: cranial nerve Present 2B Expression in this mutant is the same as in wild-type embryos.
TS19: peripheral nervous system Present 2B Expression in this mutant is the same as in wild-type embryos.
Specimen 2C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: forebrain Present Regionally restricted 2C Expression is in the mammillary tract.
TS27: anterior commissure Present 2C
TS27: fornix Present 2C
TS27: hypoglossal nucleus Present 2C
Specimen 2D: postnatal day 0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 2D Expression is present, but this mutant is missing the anterior commissure in the vicinity of the midline.
TS27: forebrain Present Regionally restricted 2D Expression is present but the mammillothalamic tract is thinner in this mutant.
TS27: fornix Present 2D Expression is present, but the fornix is dispersed.
TS27: hypoglossal nucleus Present 2D Expression is present but the nucleus is atrophied.
Specimen 2E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present 2E
TS27: fornix Present 2E
TS27: hypoglossal nucleus Present 2E
TS27: forebrain Present Regionally restricted 2E Expression is in the mammillary tract.
Specimen 2F: postnatal day 0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 2F Expression is present, but this mutant is missing the anterior commissure in the vicinity of the midline.
TS27: forebrain Present Regionally restricted 2F Expression is present but the mammillothalamic tract is thinner in this mutant.
TS27: fornix Present 2F Expression is present, but the fornix is dispersed.
TS27: hypoglossal nucleus Present 2F Expression is present, but the nucleus is atrophied.
Specimen 3A: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present 3A
Specimen 3B: postnatal day 0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 3B The anterior part of the anterior commissure is disrupted around the midline region.
Specimen 3C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present 3C
Specimen 3D: postnatal day 0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 3D The anterior part of the anterior commissure is disrupted around the midline region.
Specimen 3E: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present 3E
Specimen 3F: postnatal day 0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS27: anterior commissure Present Regionally restricted 3F The stria terminalis is disrupted around the midline region.
Specimen 3R,T: embryonic day 15.5 (more )
Note: Double labeled: green - Nefm; red - Ctnna2 (assay MGI:5547982).
Structure Level Pattern Image Note
TS23: diencephalon Present Regionally restricted 3R , 3T Expression is in the anterior commissure.
Specimen 3U,W: embryonic day 15.5 (more )
Note: Double labeled: green - Nefm; red - Ctnna2 (assay MGI:5547982).
Structure Level Pattern Image Note
TS23: diencephalon Present Regionally restricted 3U , 3V Expression is in the anterior commissure.
Specimen 5G: postnatal day 0 (more )
Note: Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
Structure Level Pattern Image Note
TS27: hypoglossal nucleus Present 5G
Specimen 5H: postnatal day 0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Note: Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
Structure Level Pattern Image Note
TS27: hypoglossal nucleus Present 5H
Specimen 5K: embryonic day 14.5 (more )
Note: Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
Structure Level Pattern Image Note
TS22: hindbrain Present 5K
Specimen 5L: embryonic day 14.5; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Note: Double labeled: green - Nefm; red - Calb1 (assay MGI:5548087).
Structure Level Pattern Image Note
TS22: hindbrain Present 5L
Specimen 5O: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nerve Present Regionally restricted 5O Staining illustrates innervations of the tongue.
TS22: tongue Present Regionally restricted 5O Staining illustrates innervations of the tongue.
Specimen 5P: embryonic day 14.5; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS22: nerve Weak Regionally restricted 5P Staining illustrates that innervation of the tongue is reduced in this mutant.
TS22: tongue Weak Regionally restricted 5P Staining illustrates that innervation of the tongue is reduced in this mutant.
Specimen 6J: postnatal day 0 (more )
Note: Double labeled: red - Nefm; green - Calb1 (assay MGI:5548087).
Structure Level Pattern Image Note
TS27: mammillary body Present 6J
Specimen 6K: postnatal day 0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Note: Double labeled: red - Nefm; green - Calb1 (assay MGI:5548087).
Structure Level Pattern Image Note
TS27: mammillary body Present 6K
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory