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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5541874
Gene symbol: Meis1
Gene name: Meis homeobox 1
Probe: RIKEN clone 6030414L06 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:13665: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: male reproductive system Present GUDMAP:13665
TS23: degenerating rest of paramesonephric duct of male Present GUDMAP:13665
TS23: epithelium of degenerating rest of paramesonephric duct of male Present GUDMAP:13665
TS23: mesenchyme of degenerating rest of paramesonephric duct of male Present GUDMAP:13665
TS23: genital tubercle of male Present GUDMAP:13665 Expression pattern switches from being present in the surface epithelium of the glans / distal genital tubercle (mesenchyme of glans absent) to the mesenchyme in the proximal genital tubercle and labioscrotal swelling (where expression in the surface epithelium is now absent). Expression in the mesenchyme of the genital tubercle is restricted from the central genital tubercle region.
TS23: scrotal swelling Present GUDMAP:13665
TS23: male external genitalia Present GUDMAP:13665
TS23: epithelium of phallic urethra of male Present GUDMAP:13665
TS23: urethral tube epithelium of male Present GUDMAP:13665
TS23: glans of male genital tubercle Present GUDMAP:13665
TS23: preputial swelling of male Present GUDMAP:13665
TS23: skin of glans of male genital tubercle Present GUDMAP:13665
TS23: skin of male preputial swelling Present Regionally restricted GUDMAP:13665
TS23: mesenchyme of male preputial swelling Present GUDMAP:13665
TS23: mesenchyme of scrotal swelling Present GUDMAP:13665
TS23: nephric duct of male, rest of Present GUDMAP:13665
TS23: urethral plate epithelium of male Ambiguous GUDMAP:13665 Possible weak expression, however only a small portion of this tissue was present in the sections.
TS23: mesenchyme of glans of male genital tubercle Absent GUDMAP:13665
TS23: scrotal swelling skin Absent GUDMAP:13665
TS23: developing vasculature of male genital tubercle Absent GUDMAP:13665
TS23: mesenchyme of nephric duct of male Present GUDMAP:13665
TS23: epithelium of nephric duct of male Present GUDMAP:13665

Specimen GUDMAP:13666: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: bladder Present GUDMAP:13666
TS23: urothelium of bladder Present GUDMAP:13666
TS23: detrusor muscle of bladder Present GUDMAP:13666
TS23: serosa of bladder Present GUDMAP:13666
TS23: adventitia of bladder Present GUDMAP:13666
TS23: urethra of male Present GUDMAP:13666
TS23: pelvic urethra of male Present GUDMAP:13666
TS23: epithelium of pelvic urethra of male Present GUDMAP:13666
TS23: phallic urethra of male Present GUDMAP:13666
TS23: urethral plate epithelium of male Present GUDMAP:13666
TS23: urothelium of bladder fundus Present GUDMAP:13666
TS23: urothelium of ventral bladder neck Present GUDMAP:13666
TS23: mesenchymal layer of pelvic urethra of male Absent GUDMAP:13666
TS23: muscle layer of pelvic urethra of male Present GUDMAP:13666
TS23: muscle layer of dorsal pelvic urethra of male Present GUDMAP:13666
TS23: muscle layer of ventral pelvic urethra of male Present GUDMAP:13666
TS23: pelvic ganglion Ambiguous GUDMAP:13666 The strong expression seen in subregions of the muscle layer of the pelvic urethra and phallic urethra may include pelvic ganglia.
TS23: urothelium of ureter Absent GUDMAP:13666 The urothelium of the ureter adjacent to the bladder shows no expression.

Specimen GUDMAP:13667: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: female reproductive system Present GUDMAP:13667
TS23: genital tubercle of female Present GUDMAP:13667 Expression pattern switches from being present in the surface epithelium of the distal genital tubercle (distal mesenchyme absent) to the mesenchyme in the proximal genital tubercle and labioscrotal swelling (where expression in the surface is now absent - although this is more obvious in the male). Also, the mesenchymal expression is absent from the center of the GT.
TS23: labial swelling Present GUDMAP:13667
TS23: female external genitalia Present GUDMAP:13667
TS23: epithelium of phallic urethra of female Present GUDMAP:13667 Expression was detected in all urethral epithelium present. Distal urethral epithelium was not present in the section examined.
TS23: urethral tube epithelium of female Present GUDMAP:13667
TS23: proximal urethral meatus of female Present GUDMAP:13667
TS23: preputial swelling of female Present GUDMAP:13667
TS23: mesenchyme of female preputial swelling Present GUDMAP:13667
TS23: glans of female genital tubercle Present GUDMAP:13667
TS23: genital tubercle mesenchyme of female Present GUDMAP:13667
TS23: skin of female preputial swelling Present Regionally restricted GUDMAP:13667
TS23: mesenchyme of labial swelling Present GUDMAP:13667
TS23: mesenchyme of glans of female genital tubercle Absent GUDMAP:13667
TS23: labial swelling skin Ambiguous GUDMAP:13667
TS23: paramesonephric duct of female, rest of Present GUDMAP:13667
TS23: epithelium of rest of paramesonephric duct of female Present GUDMAP:13667
TS23: mesenchyme of rest of paramesonephric duct of female Present GUDMAP:13667
TS23: nephric duct of female, rest of Present GUDMAP:13667
TS23: mesenchyme of nephric duct of female Present GUDMAP:13667
TS23: epithelium of nephric duct of female Absent GUDMAP:13667

Specimen GUDMAP:13668: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: bladder Present GUDMAP:13668
TS23: urothelium of bladder Present GUDMAP:13668
TS23: detrusor muscle of bladder Present GUDMAP:13668
TS23: serosa of bladder Present GUDMAP:13668
TS23: adventitia of bladder Present GUDMAP:13668
TS23: pelvic ganglion Ambiguous GUDMAP:13668 The strong expression seen in subregions of the muscle layer of the pelvic urethra and phallic urethra and neck region of the bladder may include pelvic ganglia (more obvious in the male).
TS23: urothelium of ureter Absent GUDMAP:13668 The urothelium of the ureter adjacent to the bladder shows no expression.
TS23: urethra of female Present GUDMAP:13668
TS23: pelvic urethra of female Present GUDMAP:13668
TS23: phallic urethra of female Present GUDMAP:13668
TS23: epithelium of pelvic urethra of female Present GUDMAP:13668
TS23: muscle layer of pelvic urethra of female Present GUDMAP:13668
TS23: urethral plate epithelium of female Present GUDMAP:13668
TS23: mesenchymal layer of pelvic urethra of female Absent GUDMAP:13668


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory