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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5541615
Gene symbol: Napsa
Gene name: napsin A aspartic peptidase
Probe: RIKEN clone 0610011C03 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:10917: embryonic day 15.5 (more )
Note: This assay's probe was visualized using BM purple; it is blue. The section was also subjected to immunohistochemistry with an anti-Aqp1 antibody; that labeling is orange.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:10917
TS23: metanephros Present Regionally restricted GUDMAP:10917
TS23: renal cortex Present Regionally restricted GUDMAP:10917
TS23: cortical renal tubule Present Regionally restricted GUDMAP:10917
TS23: cortical early proximal tubule Present Regionally restricted GUDMAP:10917 distal expression; strong Napsa mRNA expression in subset of early proximal tubules of maturing nephron stage IV only which overlap with Aqp1 early proximal tubule expression. Napsa expression in the early S2 and S3 segments of the early proximal tubule ie. regional expression adjacent to the immature loop of Henle or most distal early proximal tubules.
TS23: renal medulla Present GUDMAP:10917
TS23: immature loop of Henle Present Regionally restricted GUDMAP:10917 proximal expression; restricted weak expression in a very small portion of the immature loop of Henle adjacent to the early proximal tubule or cortex (a very small segment of the most proximal, early thin descending limb)
TS23: renal capsule Absent GUDMAP:10917
TS23: nephrogenic zone Absent GUDMAP:10917
TS23: renal vesicle Absent GUDMAP:10917
TS23: comma-shaped body Absent GUDMAP:10917
TS23: s-shaped body Absent GUDMAP:10917
TS23: capillary loop renal corpuscle Absent GUDMAP:10917
TS23: maturing renal corpuscle Absent GUDMAP:10917
TS23: anlage of loop of Henle of cortical renal tubule Absent GUDMAP:10917
TS23: renal connecting tubule Absent GUDMAP:10917
TS23: cortical early distal tubule Absent GUDMAP:10917
TS23: cortical collecting duct Absent GUDMAP:10917
TS23: renal cortical interstitium Absent GUDMAP:10917
TS23: renal cortical vasculature Absent GUDMAP:10917
TS23: renal pelvis Absent GUDMAP:10917
TS23: ureter Absent GUDMAP:10917
TS23: renal medullary interstitium Absent GUDMAP:10917
TS23: renal medullary vasculature Absent GUDMAP:10917
TS23: medullary collecting duct Absent GUDMAP:10917
TS23: cortical renal tubule of maturing nephron group Present Regionally restricted GUDMAP:10917
TS23: early proximal tubule of maturing nephron Present Regionally restricted GUDMAP:10917 distal expression
TS23: cortical renal tubule of capillary loop nephron group Absent GUDMAP:10917

Specimen GUDMAP:10918: postnatal adult (more )
Note: This animal was sexually mature. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: urinary system Present GUDMAP:10918
TS28: metanephros Present Regionally restricted GUDMAP:10918
TS28: renal cortex Present Regionally restricted GUDMAP:10918
TS28: cortical renal tubule Present Regionally restricted GUDMAP:10918
TS28: renal proximal tubule Present Regionally restricted GUDMAP:10918
TS28: proximal straight tubule, cortical portion Present GUDMAP:10918
TS28: renal medulla Present Regionally restricted GUDMAP:10918
TS28: outer renal medulla Present Regionally restricted GUDMAP:10918
TS28: outer stripe of outer medulla Present Regionally restricted GUDMAP:10918
TS28: loop of Henle of outer stripe of outer medulla Present Regionally restricted GUDMAP:10918
TS28: proximal straight tubule of outer stripe of outer medulla Present GUDMAP:10918
TS28: mature renal corpuscle Absent GUDMAP:10918
TS28: renal proximal convoluted tubule Absent GUDMAP:10918
TS28: renal connecting tubule Absent GUDMAP:10918
TS28: renal distal tubule Absent GUDMAP:10918
TS28: renal cortical interstitium Absent GUDMAP:10918
TS28: renal cortical vasculature Absent GUDMAP:10918
TS28: cortical collecting duct Absent GUDMAP:10918
TS28: distal straight tubule of outer stripe of outer medulla Absent GUDMAP:10918
TS28: inner stripe of outer medulla Absent GUDMAP:10918
TS28: outer medullary collecting duct Absent GUDMAP:10918
TS28: outer medullary interstitium Absent GUDMAP:10918
TS28: inner renal medulla Absent GUDMAP:10918
TS28: renal pelvis Absent GUDMAP:10918

Specimen GUDMAP:10919: postnatal adult (more )
Note: This animal was sexually mature. This assay's probe was visualized using BM purple; it is blue. The section was also subjected to immunohistochemistry with an anti-Aqp1 antibody; that labeling is orange.
Structure Level Pattern Image Note
TS28: urinary system Present GUDMAP:10919
TS28: metanephros Present Regionally restricted GUDMAP:10919
TS28: renal cortex Present Regionally restricted GUDMAP:10919
TS28: cortical renal tubule Present Regionally restricted GUDMAP:10919
TS28: renal proximal tubule Present Regionally restricted GUDMAP:10919
TS28: proximal straight tubule, cortical portion Present GUDMAP:10919
TS28: renal medulla Present Regionally restricted GUDMAP:10919
TS28: outer renal medulla Present Regionally restricted GUDMAP:10919
TS28: outer stripe of outer medulla Present Regionally restricted GUDMAP:10919
TS28: loop of Henle of outer stripe of outer medulla Present Regionally restricted GUDMAP:10919
TS28: proximal straight tubule of outer stripe of outer medulla Present GUDMAP:10919
TS28: mature renal corpuscle Absent GUDMAP:10919
TS28: renal proximal convoluted tubule Absent GUDMAP:10919
TS28: renal connecting tubule Absent GUDMAP:10919
TS28: renal distal tubule Absent GUDMAP:10919
TS28: renal cortical interstitium Absent GUDMAP:10919
TS28: renal cortical vasculature Absent GUDMAP:10919
TS28: cortical collecting duct Absent GUDMAP:10919
TS28: distal straight tubule of outer stripe of outer medulla Absent GUDMAP:10919
TS28: inner stripe of outer medulla Absent GUDMAP:10919
TS28: outer medullary collecting duct Absent GUDMAP:10919
TS28: outer medullary interstitium Absent GUDMAP:10919
TS28: inner renal medulla Absent GUDMAP:10919
TS28: renal pelvis Absent GUDMAP:10919


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory