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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5540728
Gene symbol: Ltbp1
Gene name: latent transforming growth factor beta binding protein 1
Probe: RIKEN clone 9430031G15 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:7447: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: urinary system Present GUDMAP:7447
TS20: metanephros Present GUDMAP:7447
TS20: early nephron Present GUDMAP:7447
TS20: urogenital mesentery Present GUDMAP:7447 the signal may be background
Specimen GUDMAP:7448: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: male reproductive system Present GUDMAP:7448
TS20: mesonephros of male Present GUDMAP:7448
TS20: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:7448 medial and dorsal expression; restricted to medial edge where it meets the testis and appears to be only rostral
TS20: paramesonephric duct of male, mesonephric portion Present GUDMAP:7448
TS20: urinary system mesentery Present GUDMAP:7448
TS20: nephric duct of male, mesonephric portion Absent GUDMAP:7448
TS20: testis Absent GUDMAP:7448
Specimen GUDMAP:7449: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: female reproductive system Present GUDMAP:7449
TS20: mesonephros of female Present GUDMAP:7449
TS20: mesonephric mesenchyme of female Present Regionally restricted GUDMAP:7449 medial expression; restricted to medial edge where it meets the ovary
TS20: paramesonephric duct of female, mesonephric portion Present GUDMAP:7449
TS20: urinary system mesentery Present GUDMAP:7449
TS20: nephric duct of female, mesonephric portion Absent GUDMAP:7449
TS20: nephric duct of female, rest of Absent GUDMAP:7449
TS20: ovary Absent GUDMAP:7449
Specimen GUDMAP:7450: embryonic day 10.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS17: genitourinary system Present GUDMAP:7450
TS17: mesonephric tubule Present GUDMAP:7450 may be restricted to the mesonephric glomeruli
TS17: mesonephros mesenchyme Present Regionally restricted GUDMAP:7450 rostral expression; strongest signal in the mesenchyme surrounding the nephric duct in the rostral mesonephros
TS17: metanephric mesenchyme Absent GUDMAP:7450
TS17: nephric duct, mesonephric portion Absent GUDMAP:7450
TS17: nephric duct, metanephric portion Absent GUDMAP:7450
TS17: cranial mesonephric tubule Ambiguous GUDMAP:7450
Specimen GUDMAP:7755: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: male reproductive system Present GUDMAP:7755
TS23: mesorchium Present GUDMAP:7755
TS23: testis Present GUDMAP:7755
TS23: rete testis Present GUDMAP:7755
TS23: coelomic epithelium of testis Present GUDMAP:7755
TS23: coelomic epithelium of male mesonephros Present GUDMAP:7755
TS23: mesonephros of male Present GUDMAP:7755
TS23: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:7755 expression restricted to mesenchyme surrounding the paramesonephric duct and in some sections the tissue between the duct and the edge of the mesonephros
TS23: degenerating mesonephric portion of male paramesonephric duct Present GUDMAP:7755 signal in duct epithelium and duct mesenchyme
Specimen GUDMAP:7756: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: bladder Present GUDMAP:7756
TS23: urothelium of bladder Present GUDMAP:7756 weak signal
Specimen GUDMAP:7757: postnatal adult (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: metanephros Absent GUDMAP:7757
Specimen GUDMAP:7758: postnatal adult (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: ovary Absent GUDMAP:7758
TS28: oviduct Absent GUDMAP:7758
TS28: uterus Absent GUDMAP:7758
Specimen GUDMAP:7813: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: female reproductive system Present GUDMAP:7813
TS23: mesonephros of female Present GUDMAP:7813
TS23: paramesonephric duct of female, mesonephric portion Present GUDMAP:7813 strong expression
TS23: mesonephric mesenchyme of female Present Regionally restricted GUDMAP:7813 restricted to mesenchyme surrounding paramesonephric duct
TS23: ovary Present GUDMAP:7813
TS23: mesenchymal stroma of ovary Present GUDMAP:7813
TS23: mesovarium Present GUDMAP:7813 moderate levels of expression
TS23: degenerating mesonephric portion of nephric duct of female Ambiguous GUDMAP:7813 there may be very weak signal
Specimen GUDMAP:7851: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:7851
TS23: metanephros Present GUDMAP:7851
TS23: nephrogenic zone Present GUDMAP:7851
TS23: nephrogenic interstitium Present GUDMAP:7851
TS23: cap mesenchyme Present GUDMAP:7851
TS23: renal cortex Present GUDMAP:7851
TS23: renal cortical interstitium Present GUDMAP:7851
TS23: renal medulla Present GUDMAP:7851
TS23: renal medullary interstitium Present GUDMAP:7851
TS23: immature loop of Henle Present GUDMAP:7851
TS23: renal pelvis Present GUDMAP:7851
TS23: pelvic urothelial lining Present GUDMAP:7851
TS23: pelvic smooth muscle Present GUDMAP:7851
TS23: perihilar interstitium Present GUDMAP:7851
TS23: cortical renal tubule Present GUDMAP:7851
TS23: capillary loop renal corpuscle Present GUDMAP:7851
TS23: maturing renal corpuscle Present GUDMAP:7851
TS23: renal interstitium Present GUDMAP:7851 strongest signal
TS23: collecting duct Absent GUDMAP:7851 expression appears absent from all components of the collecting duct
TS23: pretubular aggregate Ambiguous GUDMAP:7851
TS23: renal vesicle Ambiguous GUDMAP:7851
TS23: comma-shaped body Ambiguous GUDMAP:7851
TS23: s-shaped body Ambiguous GUDMAP:7851
Specimen GUDMAP:8889: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present Regionally restricted GUDMAP:8889
TS23: metanephros Present Regionally restricted GUDMAP:8889
TS23: renal capsule Present GUDMAP:8889
TS23: renal cortex Present Regionally restricted GUDMAP:8889
TS23: renal vesicle Present Ubiquitous GUDMAP:8889 expression detected in entire renal vesicle including presumptive renal connecting tubule seen extending into the ureteric tip
TS23: renal connecting tubule Present Regionally restricted GUDMAP:8889 expression only in immature renal tubules of capillary loop nephrons
TS23: comma-shaped body Present GUDMAP:8889
TS23: s-shaped body Present GUDMAP:8889
TS23: renal connecting tubule of s-shaped body Present GUDMAP:8889
TS23: distal segment of s-shaped body Present GUDMAP:8889
TS23: medial segment of s-shaped body Present GUDMAP:8889
TS23: proximal segment of s-shaped body Present GUDMAP:8889
TS23: capillary loop renal corpuscle Present Regionally restricted GUDMAP:8889
TS23: visceral epithelium of capillary loop renal corpuscle Present GUDMAP:8889
TS23: maturing renal corpuscle Present Regionally restricted GUDMAP:8889 weak expression compared with capillary loop renal corpuscle
TS23: maturing glomerular tuft Present GUDMAP:8889 weak expression compared with capillary loop renal corpuscle
TS23: visceral epithelium of maturing renal corpuscle Present GUDMAP:8889 weak expression compared with capillary loop renal corpuscle
TS23: cortical renal tubule Present Regionally restricted GUDMAP:8889 expression seen only in immature cortical renal tubules of capillary loop nephrons
TS23: cortical early proximal tubule Present Regionally restricted GUDMAP:8889 expression only in immature cortical renal tubules of capillary loop nephrons
TS23: anlage of loop of Henle of cortical renal tubule Present GUDMAP:8889
TS23: cortical early distal tubule Present Regionally restricted GUDMAP:8889 expression only in immature cortical renal tubules of capillary loop nephrons
TS23: renal cortical vasculature Present Regionally restricted GUDMAP:8889
TS23: renal cortical arterial system Present GUDMAP:8889 expression seen in smooth muscle layer of small and large renal arteries
TS23: renal medulla Present Regionally restricted GUDMAP:8889
TS23: renal medullary interstitium Present Regionally restricted GUDMAP:8889 expression in a subset of interstitium surrounding the medullary collecting ducts and tubules
TS23: renal pelvis Present Regionally restricted GUDMAP:8889
TS23: pelvic smooth muscle Present GUDMAP:8889
TS23: nephrogenic zone Absent GUDMAP:8889
TS23: pretubular aggregate Absent GUDMAP:8889 uncertain expression
TS23: nephrogenic interstitium Absent GUDMAP:8889
TS23: cap mesenchyme Absent GUDMAP:8889
TS23: ureteric tip Absent GUDMAP:8889
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:8889
TS23: cortical collecting duct Absent GUDMAP:8889
TS23: parietal epithelium of capillary loop renal corpuscle Absent GUDMAP:8889
TS23: presumptive mesangium of capillary loop renal corpuscle Absent GUDMAP:8889
TS23: presumptive endothelium of capillary loop renal corpuscle Absent GUDMAP:8889
TS23: associated interstitium of capillary loop renal corpuscle Absent GUDMAP:8889
TS23: glomerular capillary system of maturing glomerular tuft Absent GUDMAP:8889
TS23: glomerular basement membrane of maturing renal corpuscle Absent GUDMAP:8889
TS23: glomerular mesangium of maturing glomerular tuft Absent GUDMAP:8889
TS23: Bowman's capsule of maturing renal corpuscle Absent GUDMAP:8889
TS23: parietal epithelium of maturing renal corpuscle Absent GUDMAP:8889
TS23: glomerular mesangium of maturing renal corpuscle Absent GUDMAP:8889
TS23: renal cortical venous system Absent GUDMAP:8889
TS23: immature loop of Henle Absent GUDMAP:8889
TS23: medullary collecting duct Absent GUDMAP:8889
TS23: pelvic urothelial lining Absent GUDMAP:8889
TS23: renal cortical interstitium Ambiguous GUDMAP:8889
TS23: perihilar interstitium Ambiguous GUDMAP:8889
TS23: renal connecting segment of renal vesicle Present GUDMAP:8889
TS23: distal renal vesicle Present GUDMAP:8889
TS23: proximal renal vesicle Present GUDMAP:8889
TS23: cortical renal tubule of capillary loop nephron group Present GUDMAP:8889
TS23: early proximal tubule of capillary loop nephron Present GUDMAP:8889
TS23: early distal tubule of capillary loop nephron Present GUDMAP:8889
TS23: renal connecting tubule of capillary loop nephron Present GUDMAP:8889
TS23: cortical renal tubule of maturing nephron group Absent GUDMAP:8889
Specimen GUDMAP:8890: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureter Present GUDMAP:8890
TS23: ureteral mesenchyme Present GUDMAP:8890
TS23: ureteral smooth muscle layer Present GUDMAP:8890
TS23: ureteral mesenchyme outer layer Present GUDMAP:8890
TS23: urothelium of ureter Absent GUDMAP:8890
Specimen GUDMAP:9074: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: male reproductive system Present Regionally restricted GUDMAP:9074
TS21: mesonephros of male Present Regionally restricted GUDMAP:9074
TS21: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:9074
TS21: paramesonephric duct of male, mesonephric portion Present GUDMAP:9074
TS21: paramesonephric duct of male, rest of Present GUDMAP:9074
TS21: epithelium of rest of paramesonephric duct of male Present GUDMAP:9074
TS21: mesenchyme of rest of paramesonephric duct of male Present GUDMAP:9074
TS21: mesonephric tubule of male Absent GUDMAP:9074
TS21: cranial mesonephric tubule of male Absent GUDMAP:9074
TS21: mesonephric glomerulus of male Absent GUDMAP:9074
TS21: epithelium of nephric duct of male Absent GUDMAP:9074
TS21: rest of cranial mesonephric tubule of male Absent GUDMAP:9074
TS21: caudal mesonephric tubule of male Absent GUDMAP:9074
TS21: nephric duct of male, mesonephric portion Absent GUDMAP:9074
TS21: nephric duct of male, rest of Ambiguous GUDMAP:9074 possible signal in the mesenchyme
TS21: mesenchyme of nephric duct of male Ambiguous GUDMAP:9074 possible signal
TS21: coelomic epithelium of testis Ambiguous GUDMAP:9074 possible signal
TS21: interstitium of the testis Ambiguous GUDMAP:9074
TS21: testis Ambiguous GUDMAP:9074 possible signal in the coelomic epithelium or in a subset of the interstitium
Specimen GUDMAP:9075: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present Regionally restricted GUDMAP:9075
TS21: urogenital mesentery Present GUDMAP:9075
TS21: metanephros Present Regionally restricted GUDMAP:9075
TS21: nephrogenic zone Present Regionally restricted GUDMAP:9075
TS21: early nephron Present GUDMAP:9075
TS21: cap mesenchyme Absent GUDMAP:9075
TS21: ureteric tip Absent GUDMAP:9075
TS21: pretubular aggregate Ambiguous GUDMAP:9075
TS21: renal capsule Ambiguous GUDMAP:9075 possible expression as seen in the metanephros on the right; the capsule may have been removed from the left metanephros
Specimen GUDMAP:9076: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present GUDMAP:9076
TS21: urogenital sinus Present GUDMAP:9076 possible expression in the rostral urogenital sinus
TS21: primitive bladder Ambiguous GUDMAP:9076 possible expression
Specimen GUDMAP:9077: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: female reproductive system Present Regionally restricted GUDMAP:9077
TS20: mesonephros of female Present Regionally restricted GUDMAP:9077
TS20: mesonephric mesenchyme of female Present GUDMAP:9077
TS20: paramesonephric duct of female, mesonephric portion Present GUDMAP:9077
TS20: ovary Present GUDMAP:9077 weak signal
TS20: mesonephric tubule of female Ambiguous GUDMAP:9077
TS20: nephric duct of female, mesonephric portion Ambiguous GUDMAP:9077
Specimen GUDMAP:9078: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: urinary system Present Regionally restricted GUDMAP:9078
TS20: urogenital mesentery Present GUDMAP:9078
TS20: metanephros Present Regionally restricted GUDMAP:9078
TS20: early nephron Present GUDMAP:9078
TS20: nephrogenic zone Present GUDMAP:9078
Specimen GUDMAP:13634: postnatal adult (more )
Note: This animal was sexually mature. Labeling was visualized using BM purple. Moderate expression was seen with the low level expression control (Shh). Thus, low levels of mRNA expression should be detectable in this experiment.
Structure Cell Type Level Pattern Image Note
TS28: male reproductive system Present GUDMAP:13634
TS28: reproductive system Present GUDMAP:13634
TS28: testis Present GUDMAP:13634
TS28: seminiferous tubule Present GUDMAP:13634
TS28: Sertoli cell Sertoli cell Absent GUDMAP:13634
TS28: spermatogonium Absent GUDMAP:13634
TS28: peritubular myoid cell peritubular myoid cell Absent GUDMAP:13634
TS28: epididymis Absent GUDMAP:13634
TS28: interstitium of the testis Absent GUDMAP:13634
TS28: surface epithelium of testis Absent GUDMAP:13634
TS28: vasculature of testis Absent GUDMAP:13634
TS28: tunica albuginea of testis Absent GUDMAP:13634
TS28: spermatocyte Ambiguous GUDMAP:13634
TS28: spermatid Ambiguous GUDMAP:13634
TS28: spermatozoon Absent GUDMAP:13634
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04/23/2024
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