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Gene Expression Data
Assay Details
Assay
Reference: J:138735 Okada Y, et al., A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo. Blood. 2008 Sep 15;112(6):2336-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5532551
Gene symbol: Robo4
Gene name: roundabout guidance receptor 4
Reporter: lacZ
Direct Detection
Results
Specimen 2B Brain: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present 2B Brain Expression is greater in microvascular endothelium compared with endothelial cells of large arteries or veins.

Specimen 2B Brain ETSmut: postnatal week 6-8; Robo4tm2Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Weak 2B Brain ETSmut

Specimen 2B Lung: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present 2B Lung Expression is greater in microvascular endothelium compared with endothelial cells of large arteries or veins.

Specimen 2B Lung ETSmut: postnatal week 6-8; Robo4tm2Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Weak 2B Lung ETSmut

Specimen 2B Diaphragm: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present 2B Diaphragm Expression is greater in microvascular endothelium compared with endothelial cells of large arteries or veins.

Specimen 2B Diaphragm ETSmut: postnatal week 6-8; Robo4tm2Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Weak 2B Diaphragm ETSmut

Specimen 2B Sk. Muscle: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present 2B Sk. Muscle Expression is greater in microvascular endothelium compared with endothelial cells of large arteries or veins.

Specimen 2B Sk. Muscle ETSmut: postnatal week 6-8; Robo4tm2Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Weak 2B Sk. Muscle ETSmut

Specimen 2B right Heart: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present 2B right Heart Expression is greater in microvascular endothelium compared with endothelial cells of large arteries or veins.

Specimen 2B right Heart ETSmut: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Weak 2B right ETSmut Heart

Specimen 2B right Lung: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present 2B right Lung Expression is greater in microvascular endothelium compared with endothelial cells of large arteries or veins.

Specimen 2B right Lung ETSmut: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Weak 2B right ETSmut Lung

Specimen 2B right Traceha: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present 2B right Trachea Expression is greater in microvascular endothelium compared with endothelial cells of large arteries or veins.

Specimen 2B right Trachea ETSmut: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Weak 2B right ETSmut Trachea

Specimen 2B right Aorta: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: blood vessel endothelium Present 2B right Aorta Expression is greater in microvascular endothelium compared with endothelial cells of large arteries or veins.

Specimen 2B right Aorta ETSmut: postnatal week 6-8; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS28: aorta Weak 2B right ETSmut Aorta

Specimen 2F top left: embryonic day 10.0; Robo4tm1Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS16: embryo Present 2F left

Specimen 2F top: embryonic day 10.0; Robo4tm2Aird/Robo4+ (more )
Structure Level Pattern Image Note
TS16: embryo Weak 2F top ETSmut


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory