Robo4^tm2Aird
Targeted Allele Detail

Summary

• Symbol: Robo4^tm2Aird
• Name: roundabout guidance receptor 4; targeted mutation 2, William C Aird
• MGI ID: MGI:3808845
• Gene: Robo4 Location: Chr9:37313198-37325319 bp, + strand Genetic Position: Chr9, 20.76 cM
• Alliance: Robo4^tm2Aird page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138735
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 3 were replaced with a lacZ and neo cassette and the ETS site at -119 was mutated. No details are provided. (J:138735)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Robo4 Mutation: 87 strains or lines available

References

• Original: J:138735 Okada Y, et al., A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo. Blood. 2008 Sep 15;112(6):2336-9
• All: 1 reference(s)