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Gene Expression Data
Assay Details
Assay
Reference: J:119933 Lewis SL, et al., Genetic interaction of Gsc and Dkk1 in head morphogenesis of the mouse. Mech Dev. 2007 Feb;124(2):157-165
Assay type: RNA in situ
MGI Accession ID: MGI:5532337
Gene symbol: Hesx1
Gene name: homeobox gene expressed in ES cells
Probe: Hesx1 probe10
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4C left: embryonic day 8.5 (more )
Note: Early somite-stage embryo.
Structure Level Pattern Image Note
TS13: future prosencephalon Present 4C Hesx1 lateral view
Specimen 4C right: embryonic day 8.5 (more )
Note: Early somite-stage embryo.
Structure Level Pattern Image Note
TS13: future prosencephalon Present 4C Hesx1 en face view
Specimen 4D left: embryonic day 8.5; Dkk1tm1Lmgd/Dkk1+, Gsctm2Bhr/Gsctm2Bhr (more )
Note: Early somite-stage embryo. Double labeled: purple - Hesx1; blue - Gsc (assay MGI:5532320).
Structure Level Pattern Image Note
TS13: future prosencephalon Present 4D Hesx1 lateral view Expression was reduced in the forebrain of the mutant.
Specimen 4D right: embryonic day 8.5; Dkk1tm1Lmgd/Dkk1+, Gsctm2Bhr/Gsctm2Bhr (more )
Note: Early somite-stage embryo. Double labeled: purple - Hesx1; blue - Gsc (assay MGI:5532320).
Structure Level Pattern Image Note
TS13: future prosencephalon Present 4D Hesx1 en face view Expression was reduced in the forebrain of the mutant.
Specimen 4E left: embryonic day 8.0 (more )
Note: Early head-fold embryo.
Structure Level Pattern Image Note
TS12: future prosencephalon Present Regionally restricted 4E Wildtype Expression was detected in the neural plate.
Specimen 4E middle: embryonic day 8.0; Gsctm2Bhr/Gsc+ (more )
Note: Early head-fold embryo.
Structure Level Pattern Image Note
TS12: future prosencephalon Present Regionally restricted 4E Dkk1+/+;Gsc+/lacZ Expression was detected in the neural plate.
Specimen 4E right: embryonic day 8.0; Dkk1tm1Lmgd/Dkk1+, Gsctm2Bhr/Gsc+ (more )
Note: Early head-fold embryo.
Structure Level Pattern Image Note
TS12: future prosencephalon Present Regionally restricted 4E Dkk1+/-;Gsc+/lacZ The expression domain was reduced in the neural plate of the compound heterozygote.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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