Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gabrdtm1.1Jmag
Name:	gamma-aminobutyric acid (GABA) A receptor, subunit delta; targeted mutation 1.1, Jamie Maguire
MGI ID:	MGI:5526859
Gene:	Gabrd  Location: Chr4:155469436-155482549 bp, - strand  Genetic Position: Chr4, 86.17 cM
Alliance:	Gabrdtm1.1Jmag page

Germline Transmission:	Earliest citation of germline transmission: J:203336
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A targeting vector containing a FRT site flanked PGK-NEO cassette and a loxP site was inserted into exon 6 of the targeted gene, and another loxP site was inserted upstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exons 2 through 5 and a portion of exon 6 floxed. (J:203336)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gabrd Mutation:	30 strains or lines available

Original:	J:203336 Lee V, et al., Impact of inhibitory constraint of interneurons on neuronal excitability. J Neurophysiol. 2013 Dec;110(11):2520-35
All:	5 reference(s)