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Gene Expression Data
Assay Details
Assay
Reference: J:58233 Eisenstat DD, et al., DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation. J Comp Neurol. 1999 Nov 15;414(2):217-37
Assay type: RNA in situ
MGI Accession ID: MGI:5523863
Gene symbol: Dlx1
Gene name: distal-less homeobox 1
Probe: Dlx1 cDNA6
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 2B Expression is in the subcortical telencephalon, itincludes the large ganglionic eminence, the medial ganglionic eminence, the preoptic area, the anterior entopeduncular area, and parts of the septal and amygdalar primordia.
TS18: diencephalon Present Regionally restricted 2B Expression is in the rostral diencephalon and hypothalamus just anterior of the zona limitans intrathalamica, extending through the ventral thalamus, the supraoptoparaventricular area, the hypothalamic cell cord, and ending in the suprachiasmatic area.
TS18: diencephalon lateral wall mantle layer Present 2B
TS18: telencephalon mantle layer Present 2B
TS18: diencephalon lateral wall ventricular layer Present 2B
TS18: telencephalon ventricular layer Present 2B

Specimen 2H: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon mantle layer Present 2H
TS18: telencephalon ventricular layer Present 2H

Specimen 2N: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: telencephalon ventricular layer Present 2N
TS18: telencephalon mantle layer Present 2N

Specimen 3B: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3B Expression is in the rostral diencephalon and hypothalamus just anterior of the zona limitans intrathalamica, extending through the ventral thalamus, the supraoptoparaventricular area, the hypothalamic cell cord, and ending in the suprachiasmatic area.

Specimen 3E: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3E Expression is in the supraoptoparaventricular area and ventral thalamus with a caudal limit at the zona limitans intrathalamica.

Specimen 3O: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: diencephalon Present Regionally restricted 3O Expression is in the hypothalamus.

Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 4B
TS20: ganglionic eminence Present 4B

Specimen 4H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 4H Expression is in nascent nuclei within prosomere 3 and 4 and in periventricular cell populations that may contribute to the zona incerta and to the paraventricular nucleus.

Specimen 5H: embryonic day 11.0 (more )
Note: Double labeled: blue/purple - Dlx1; brown/red - Dlx2 (assay MGI:5523056).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5H Expression is in the medial ganglionic eminence (ventricular zone and subventricular zone).

Specimen 5I: embryonic day 11.0 (more )
Note: Double labeled: blue/purple - Dlx1; brown/red - Dlx2 (assay MGI:5523056).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5I Expression is in the medial ganglionic eminence (shown is the ventricular zone).

Specimen 5J: embryonic day 11.0 (more )
Note: Double labeled: blue/purple - Dlx1; brown/red - Dlx2 (assay MGI:5523056).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5J Expression is in the medial ganglionic eminence (shown is the subventricular zone).

Specimen 5K: embryonic day 11.0 (more )
Note: Double labeled: blue/purple - Dlx1; brown/red - Dlx1 (assay MGI:5523861).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5K Expression is in the medial ganglionic eminence (shown is the ventricular zone).

Specimen 5L: embryonic day 11.0 (more )
Note: Double labeled: blue/purple - Dlx1; brown/red - Dlx1 (assay MGI:5523861).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5L Expression is in the medial ganglionic eminence (shown is the subventricular zone).

Specimen 5M: embryonic day 11.0 (more )
Note: Double labeled: blue/purple - Dlx1; brown/red - Dlx5 (assay MGI:5523862).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5M Expression is in the medial ganglionic eminence (shown is the ventricular zone).

Specimen 5N: embryonic day 11.0 (more )
Note: Double labeled: blue/purple - Dlx1; brown/red - Dlx5 (assay MGI:5523862).
Structure Level Pattern Image Note
TS18: telencephalon Present Regionally restricted 5N Expression is in the medial ganglionic eminence (shown is the subventricular zone).

Specimen 9A +/+: embryonic day 10.5 (more )
Note: Hemisected embryos
Structure Level Pattern Image Note
TS17: branchial arch Present 9A +/+
TS17: telencephalon Present 9A +/+

Specimen 9A -/-: embryonic day 10.5; Dlx2tm1Jlr/Dlx2tm1Jlr (more )
Note: Hemisected embryos
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 9A -/- The subpallial telencephalon has a reduced area of expression in this mutant.
TS17: branchial arch Weak 9A -/-

Specimen 9B +/+: embryonic day 10.5 (more )
Note: Hemisected embryos
Structure Level Pattern Image Note
TS17: branchial arch Present 9B +/+
TS17: telencephalon Present 9B +/+

Specimen 9B -/-: embryonic day 10.5; Dlx2tm1Jlr/Dlx2tm1Jlr (more )
Note: Hemisected embryos
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 9B -/- The subpallial telencephalon has a reduced area of expression in this mutant.
TS17: branchial arch Weak 9B -/-

Specimen 9C: embryonic day 10.5 (more )
Note: Hemisected embryos
Structure Level Pattern Image Note
TS17: telencephalon Present 9C

Specimen 9D: embryonic day 10.5; Dlx2tm1Jlr/Dlx2tm1Jlr (more )
Note: Hemisected embryos
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 9D The subpallial telencephalon has a reduced area of expression in this mutant.

Specimen 9G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 9G Expression is in the ganglionic eminence primarily subpially with a few cells in the ventricular zone.

Specimen 9I: embryonic day 10.5; Dlx2tm1Jlr/Dlx2tm1Jlr (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 9I There are fewer expressing cells in the ventricular zone of the lateral ganglionic eminence in this mutant.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory