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Gene Expression Data
Assay Details
Assay
Reference: J:125089 Bi W, et al., Rai1 deficiency in mice causes learning impairment and motor dysfunction, whereas Rai1 heterozygous mice display minimal behavioral phenotypes. Hum Mol Genet. 2007 Aug 1;16(15):1802-13
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5523464
Gene symbol: Rai1
Gene name: retinoic acid induced 1
Reporter: lacZ
Direct Detection
Results
Specimen 1A: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Present 1A
TS28: hippocampus Present 1A
TS28: brain Weak Widespread 1A Expression was throughout the brain in low level.

Specimen 1B: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 1B
TS28: hippocampus CA1 Strong 1B
TS28: hippocampus CA2 Strong 1B
TS28: hippocampus CA3 Strong 1B

Specimen 1C: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 1C

Specimen 1D: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: lateral ventricle choroid plexus Strong Regionally restricted 1D Expressed in the the epithelial membrane lining the ventricle.
TS28: lateral ventricle ependyma Strong Regionally restricted 1D Expressed in the the epithelial membrane lining the ventricle.
TS28: corpus striatum Strong 1D

Specimen 1E: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: accumbens nucleus Strong 1E

Specimen 1F: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong Regionally restricted 1F Expressed in the neurons.
TS28: brain blood vessel Strong Widespread 1F Expressed in the endothelial cells of blood vessels throughout the brain.

Specimen 1G: postnatal day 7; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Strong 1G
TS28: hippocampus Strong 1G
TS28: brain Present 1G Expressed in a broader pattern than in adult mice.

Specimen 1H: postnatal day 20; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: cerebellum Strong 1H
TS28: hippocampus Strong 1H
TS28: brain Present 1H Expressed in a broader pattern than in adult mice.

Specimen 2A: postnatal day 20; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: thymus Present 2A

Specimen 2B: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: bronchiole Present 2B

Specimen 2C: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: bronchiole Present 2C

Specimen 2D: postnatal day 20; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: epididymis Present 2D
TS28: testis Present 2D

Specimen 2E: postnatal day 20; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: epididymis Present Regionally restricted 2E Expressed in the tubules.

Specimen 2F: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: ovary follicle Present 2F

Specimen 2G: postnatal day 1; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS27: metanephros Present 2G

Specimen 2H: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: collecting duct Present 2H

Specimen 2I: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: spleen Weak Single cells 2I Expressed in very few subsets of cells.

Specimen 2J: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: liver Weak Single cells 2J Expressed in very few subsets of cells.

Specimen 2K: postnatal day 20; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: hair follicle Present 2K

Specimen 2L: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: tongue Present 2L

Specimen 2M: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: spinal cord central canal Present Regionally restricted 2M Likely expressed in the ependymal cells.
TS28: spinal cord gray matter Present Regionally restricted 2M Expressed in the posterior horn.

Specimen 2N: embryonic day 18.5; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS26: spinal cord Present 2N

Specimen not shown: postnatal adult; Rai1tm1Jrl/Rai1+ (more )
Structure Level Pattern Image Note
TS28: intestine Present
TS28: submandibular gland Present
TS28: heart Weak Single cells Expressed in very few subsets of cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory