Gene Expression Data
Assay Details
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Assay
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Reference:
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J:141686
Jin C, et al., GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development. Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4245-53
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5522910
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Gene symbol:
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Lgr4
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Gene name:
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leucine-rich repeat-containing G protein-coupled receptor 4
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2A,A',A":
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lgr4Gt(LST020)Byg/Lgr4+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: eye |
Strong |
Regionally restricted |
2A'
,
2A"
,
2A
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High expression was detected in the epithelium and mesenchymal cells of the eyelid and in the groove between the eyelid and eyeball. Intense expression was also noted in the eyeball.
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Specimen
2B,B',B":
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lgr4Gt(LST020)Byg/Lgr4+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: eye |
Present |
Regionally restricted |
2B
,
2B'
,
2B"
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Expression was detected in most of the eyeball.
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| TS22: upper eyelid epithelium |
Present |
Regionally restricted |
2B'
,
2B
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Expression was detected in the basal layer of the epithelium of the eyelid.
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| TS22: upper eyelid mesenchyme |
Present |
Regionally restricted |
2B
,
2B'
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Expression was detected in the mesenchymal cells of the eyelid tip.
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| TS22: lower eyelid epithelium |
Present |
Regionally restricted |
2B"
,
2B
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Expression was detected in the basal layer of the epithelium of the eyelid.
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| TS22: lower eyelid mesenchyme |
Present |
Regionally restricted |
2B
,
2B"
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Expression was detected in the mesenchymal cells of the eyelid tip.
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Specimen
2C,C':
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Lgr4Gt(LST020)Byg/Lgr4+
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: eyelid epithelium |
Present |
Regionally restricted |
2C
,
2C'
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Expression was detected in the basal layer of the epithelium.
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| TS24: eyelid mesenchyme |
Present |
Regionally restricted |
2C
,
2C'
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Expression was detected in the mesenchymal cells close to the fused area between the upper and lower eyelids.
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Analysis Tools
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