Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Clstn3tm1.1Amcr
Name:	calsyntenin 3; targeted mutation 1.1, Ann Marie Craig
MGI ID:	MGI:5521290
Synonyms:	Clstn3-
Gene:	Clstn3  Location: Chr6:124407715-124441743 bp, - strand  Genetic Position: Chr6, 59.15 cM
Alliance:	Clstn3tm1.1Amcr page

Germline Transmission:	Earliest citation of germline transmission: J:201987
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre and Flp recombinase mediated recombination removed exon 2, 3 and neo cassette. Immunoflorescence in brain sections and western blot analysis of whole brain homogenates confirmed the absence of expression in homozygous mice. (J:201987)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Clstn3 Mutation:	65 strains or lines available

Original:	J:201987 Pettem KL, et al., The Specific alpha-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development. Neuron. 2013 Oct 2;80(1):113-28
All:	1 reference(s)