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Prss37tm1Zgwg
Targeted Allele Detail
Summary
Symbol: Prss37tm1Zgwg
Name: serine protease 37; targeted mutation 1, Zhugang Wang
MGI ID: MGI:5520954
Gene: Prss37  Location: Chr6:40491757-40496418 bp, - strand  Genetic Position: Chr6, 18.82 cM, cytoband B2
Alliance: Prss37tm1Zgwg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202066
Parent Cell Line:  PRX-129S6 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced exons 3 and 4. Western blot analysis confirmed the absence of protein expression in the testis. (J:202066)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prss37 Mutation:  16 strains or lines available
References
Original:  J:202066 Shen C, et al., Prss37 is required for male fertility in the mouse. Biol Reprod. 2013 May;88(5):123
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory