Summary | Transgene origin | Transgene description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Spaca6Tg(Tyr)Bart97bCeb
Name:	sperm acrosome associated 6; transgene insertion Bart97b, Colin E Bishop
MGI ID:	MGI:5514186
Synonyms:	Bart97b
Gene:	Spaca6  Location: Chr17:18047420-18063271 bp, + strand  Genetic Position: Chr17, 10.5 cM, cytoband A3.1
Alliance:	Spaca6Tg(Tyr)Bart97bCeb page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The insertion of a transgene containing a 4.1kb tyrosinase mini gene under the control of the tyrosinase promoter in line Bart97b produced a 11kb deletion spanning 6 exons (chr17:17,848,861-17,849,039 based on the GRCm38/mm10 assembly). RT-PCR confirmed complete absence of RNA transcripts in homozygous testis. (J:216863)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spaca6 Mutation:	37 strains or lines available

Original:	J:216863 Lorenzetti D, et al., A transgenic insertion on mouse chromosome 17 inactivates a novel immunoglobulin superfamily gene potentially involved in sperm-egg fusion. Mamm Genome. 2014 Apr;25(3-4):141-8
All:	1 reference(s)