Phenotypes associated with this allele

• Allele Symbol: Spaca6^{Tg(Tyr)Bart97bCeb}
• Allele Name: transgene insertion Bart97b, Colin E Bishop
• Allele ID: MGI:5514186
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spaca6^Tg(Tyr)Bart97bCeb/Spaca6^Tg(Tyr)Bart97bCeb	FVB/N-Spaca6^Tg(Tyr)Bart97bCeb	MGI:5609864

Genotype
MGI:5609864

hm1

• Allelic Composition: Spaca6^{Tg(Tyr)Bart97bCeb}/Spaca6^{Tg(Tyr)Bart97bCeb}
• Genetic Background: FVB/N-Spaca6^{Tg(Tyr)Bart97bCeb}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

male infertility ( J:216863 )

♂ • males fail to sire offspring when mated with wild-type FVB/N females

♂ • males, however exhibit normal mating behavior, normal sperm counts and normal testes histology

♂ • females are fertile

impaired fertilization ( J:216863 )

• wild-type superovulated females that are mated with mutant homozygous males show spermatozoa in the oviduct and ampulla but no fertilized eggs are observed, indicating a defect in sperm-egg interactions

• mutant spermatozoa accumulate in the perivitelline space of unfertilized wild-type oocytes indicating that spermatozoa are unable to fuse with the egg