Results
|
Specimen
2A:
embryonic day 9.5; Foxc1tm1Blh/Foxc1 +
(more )
Specimen
2A:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1+
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Specimen
2B:
embryonic day 9.5; Foxc1tm1Blh/Foxc1 +
(more )
Specimen
2B:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1+
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: tail unsegmented mesenchyme |
Strong |
|
2B
|
Expression is strongest in somitomere 2.
|
TS15: sclerotome |
Present |
Regionally restricted |
2B
|
As somites differentiate the expression decreases and becomes restricted to the sclerotome.
|
TS15: somite |
Present |
Regionally restricted |
2B
|
As somites differentiate the expression decreases and becomes restricted to the sclerotome.
|
Specimen
2C:
embryonic day 10.5; Foxc1tm1Blh/Foxc1 +
(more )
Specimen
2C:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1+
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: head mesenchyme |
Present |
|
2C
|
Expression includes the mesenchyme around the nasal epithelium and eye.
|
TS17: branchial arch |
Present |
|
2C
|
|
TS17: forelimb bud mesenchyme |
Present |
|
2C
|
|
TS17: heart |
Present |
|
2C
|
|
TS17: axial skeleton |
Present |
|
2C
|
Expression is in the condensing prechondrogenic mesenchyme of the future axial and appendicular skeleton, including the vertebrae, limbs, ribs, and sternum.
|
TS17: skeleton |
Present |
|
2C
|
Expression is in the condensing prechondrogenic mesenchyme of the future axial and appendicular skeleton, including the vertebrae, limbs, ribs, and sternum.
|
TS17: vertebral cartilage condensation |
Present |
|
2C
|
Expression is in the condensing prechondrogenic mesenchyme of the future axial and appendicular skeleton, including the vertebrae, limbs, ribs, and sternum.
|
Specimen
2D:
embryonic day 12.5; Foxc1tm1Blh/Foxc1 +
(more )
Specimen
2D:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: axial skeleton |
Present |
|
2D
|
Expression is in the condensing prechondrogenic mesenchyme of the future axial and appendicular skeleton, including the vertebrae, limbs, ribs, and sternum.
|
TS20: forelimb mesenchyme |
Present |
|
2D
|
Expression is in the condensing prechondrogenic mesenchyme of the future axial and appendicular skeleton, including the vertebrae, limbs, ribs, and sternum.
|
TS20: hindlimb mesenchyme |
Present |
|
2D
|
Expression is in the condensing prechondrogenic mesenchyme of the future axial and appendicular skeleton, including the vertebrae, limbs, ribs, and sternum.
|
TS20: rib pre-cartilage condensation |
Present |
|
2D
|
Expression is in the condensing prechondrogenic mesenchyme of the future axial and appendicular skeleton, including the vertebrae, limbs, ribs, and sternum.
|
TS20: skeleton |
Present |
|
2D
|
Expression is in the condensing prechondrogenic mesenchyme of the future axial and appendicular skeleton, including the vertebrae, limbs, ribs, and sternum.
|
TS20: vertebral cartilage condensation |
Present |
|
2D
|
Expression is in the condensing prechondrogenic mesenchyme of the future axial and appendicular skeleton, including the vertebrae, limbs, ribs, and sternum.
|
TS20: head mesenchyme |
Strong |
Regionally restricted |
2D
|
Expression is in the mesenchyme of the branchial arches, around the nasal epithelium and eye.
|
Specimen
2E,F,G,H,I:
embryonic day 11.5; Foxc1tm1Blh/Foxc1 +
(more )
Note: (F-I) Higher magnification of the regions indicated in (E).
Specimen
2E,F,G,H,I:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1+
|
Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
(F-I) Higher magnification of the regions indicated in (E).
|
Structure |
Level |
Pattern |
Image |
Note |
TS19: blood vessel |
Present |
|
2E
,
2F
|
Expression is in the head mesenchyme, including the developing meninges and blood vessels, and blood vessels in the neuroepithelium.
|
TS19: head mesenchyme |
Present |
|
2E
,
2F
|
Expression is in the head mesenchyme, including the developing meninges and blood vessels, and blood vessels in the neuroepithelium.
|
TS19: endocardial lining |
Present |
|
2E
,
2G
|
|
TS19: mesonephric tubule |
Strong |
|
2H
,
2E
|
|
TS19: mesonephros mesenchyme |
Strong |
|
2H
,
2E
|
|
TS19: somite |
Present |
Regionally restricted |
2I
,
2E
|
Expression is in early epithelial somites.
|
TS19: sclerotome |
Present |
|
2E
,
2I
|
|
TS19: tail unsegmented mesenchyme |
Present |
|
2E
,
2I
|
|
Specimen
2J:
embryonic day 12.5; Foxc1tm1Blh/Foxc1 +
(more )
Specimen
2J:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Specimen
2K:
embryonic day 12.5; Foxc1tm1Blh/Foxc1 +
(more )
Specimen
2K:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: skeleton |
Present |
Regionally restricted |
2K
|
Expression is in the condensing mesenchyme of the sternum primordium.
|
TS20: rib pre-cartilage condensation |
Present |
Regionally restricted |
2K
|
Expression is in the perichondrium of the ribs and is down-regulated in the undifferentiated chondrocytes.
|
Specimen
4A:
embryonic day 12.5; Foxc1tm1Blh/Foxc1 +
(more )
Specimen
4A:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1+
|
Age:
|
embryonic day 12.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: eye |
Present |
Regionally restricted |
4A
|
Expression is in periocular mesenchyme and in the ectoderm of the future inner eyelids.
|
TS20: cornea |
Present |
Single cells |
4A
|
|
TS20: hyaloid vascular plexus |
Present |
Regionally restricted |
4A
|
Expression is in endothelial cells.
|
Specimen
7A:
embryonic day 13.5; Foxc1tm1Blh/Foxc1 +
(more )
Specimen
7A:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1+
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: hindbrain meninges |
Present |
Regionally restricted |
7A
|
Expression is in arachnoid cells.
|
TS21: head mesenchyme |
Present |
Regionally restricted |
7A
|
Expression is in mesenchyme overlying the meninges' arachnoid cells.
|
Specimen
7B:
(close )
Genetic Background:
|
involves: 129S6/SvEvTac * Black Swiss
|
Mutant Allele(s):
|
Foxc1tm1Blh/Foxc1tm1Blh
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
|