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Gene Expression Data
Assay Details
Assay
Reference: J:183957 Wu F, et al., Onecut 1 and Onecut 2 are potential regulators of mouse retinal development. J Comp Neurol. 2012 Apr 1;520(5):952-69
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5509329
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: clone 39.4D5
Detection system: Secondary antibody
Results
Specimen 4C,C',C''': embryonic day 12.5 (more )
Note: Double labeled: magenta - Isl1; green - Onecut2 (assay MGI:5509317).
Structure Level Pattern Image Note
TS20: retina Present Regionally restricted 4C''' , 4C' , 4C Expression in the ganglion cell layer overlapped completely with expression of Oc2, but only a proportion of Oc2-positive cells expressed Isl1 in the neuroblast layer.
Specimen 4D,D',D''': embryonic day 14.5 (more )
Note: Double labeled: magenta - Isl1; green - Onecut2 (assay MGI:5509317).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 4D , 4D''' , 4D' Overlapping expression with Oc2 in the ganglion cell layer continued at E14.5, but there was little overlap in expression in the neuroblast layer.
Specimen not shown E12.5: embryonic day 12.5 (more )
Note: Also stained for Onecut1 (assay MGI:5509316).
Structure Level Pattern Image Note
TS20: retina Present Regionally restricted There was overlap of expression with Oc1 in both the ganglion cell layer and the neuroblast layer.
Specimen not shown E14.5: embryonic day 14.5 (more )
Note: Also stained for Onecut1 (assay MGI:5509316).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted There was overlap of expression with Oc1 in both the ganglion cell layer and the neuroblast layer.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory