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Gene Expression Data
Assay Details
Assay
Reference: J:180120 Chauhan BK, et al., Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18289-94
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5485420
Gene symbol: Rac1
Gene name: Rac family small GTPase 1
Antibody: Anti-Rac1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 3K left: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Present 3K left Expressed at both the apex and the base of the epithelial cells.
Specimen 3K right: embryonic day 10.5; Rhoatm1Yuyo/Rhoatm1Yuyo, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: lens pit Present 3K right Expression is not significantly increased apically, but is significantly increased basally.
Specimen S2 D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: eye mesenchyme Present S2_D
TS17: eye surface ectoderm Present S2_D
TS17: lens pit Present S2_D
Specimen S2 E: embryonic day 10.5; Rac1tm1Djk/Rac1tm1Djk, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: lens pit Absent S2_E Expression in the surface ectoderm adjacent to the lens pit is also absent.
TS17: eye mesenchyme Present S2_E
Specimen S2 F/H/J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: eye mesenchyme Present S2_F , S2_H
TS17: lens pit Present S2_F , S2_H
TS17: eye surface ectoderm Present S2_F , S2_H , S2_J
Specimen S2 G/I/K: embryonic day 10.5; Rac1tm1Djk/Rac1tm1Djk, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: lens pit Absent S2_G , S2_K , S2_I Expression in the surface ectoderm adjacent to the lens pit is also absent.
TS17: eye mesenchyme Present S2_G , S2_I
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory