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Gene Expression Data
Assay Details
Assay
Reference: J:171566 Kim E, et al., Regulation of cellular calcium in vestibular supporting cells by otopetrin 1. J Neurophysiol. 2010 Dec;104(6):3439-50
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5478602
Gene symbol: Otop1
Gene name: otopetrin 1
Reporter: lacZ
Antibody: anti-B-galactosidase (Abcam)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Fixative was 0.2% glutaraldehyde.
Results
Specimen 3,E,F: embryonic day 16.5; Otop1tm1Dor/Otop1tm1Dor (more )
Note: Double labeled: green - Otop1 reporter; red - Otop1 protein (assay MGI:5476800).
Structure Level Pattern Image Note
TS24: saccule Present Regionally restricted 3E , 3F Expression is near the apical surface in supporting cells in the extrastriolar regions of the sensory epithelium.
TS24: utricle Present Regionally restricted 3E , 3F Expression is near the apical surface in supporting cells in the extrastriolar regions of the sensory epithelium.
Specimen not shown: embryonic day 18.5; Otop1tm1Dor/Otop1tm1Dor (more )
Structure Level Pattern Image Note
TS26: endolymphatic sac Present
TS26: cochlea Absent
TS26: crista ampullaris Absent
Specimen S2,C,D: postnatal; Otop1tm1Dor/Otop1tm1Dor (more )
Note: Double labeled: green - Otop1; red - Myo7a (assay MGI:5476764).
Structure Level Pattern Image Note
TS28: macula of saccule Present Regionally restricted S2D , S2C Signals are absent in the striola.
TS28: macula of utricle Present Regionally restricted S2D , S2C Signals are absent in the striola.
Specimen S2 G,H: postnatal; Otop1tm1Dor/Otop1tm1Dor (more )
Note: Double labeled: green - Otop1; red - Tectb (assay MGI:5478591).
Structure Level Pattern Image Note
TS28: macula of saccule Present Regionally restricted S2H , S2G Signals are absent in the striola.
TS28: macula of utricle Present Regionally restricted S2H , S2G Signals are absent in the striola.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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