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Gene Expression Data
Assay Details
Assay
Reference: J:180706 Gruber R, et al., MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway. Nat Cell Biol. 2011 Nov;13(11):1325-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5476924
Gene symbol: H2ax
Gene name: H2A.X variant histone
Results
Specimen S3a ctr: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain ventricular layer Present S3a Mcph1-ctr
Specimen S3a del: embryonic day 15.5; Mcph1tm1.1Zqw/Mcph1tm1.1Zqw (more )
Structure Level Pattern Image Note
TS23: brain ventricular layer Present S3a Mcph1-del There was no increase in immunopositive foci in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory