Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Flvcr1tm1Etol
Name:	feline leukemia virus subgroup C cellular receptor 1; targeted mutation 1, Emanuela Tolosano
MGI ID:	MGI:5474636
Synonyms:	Flvcr1a-
Gene:	Flvcr1  Location: Chr1:190738044-190758355 bp, - strand  Genetic Position: Chr1, 96.28 cM
Alliance:	Flvcr1tm1Etol page

Germline Transmission:	Earliest citation of germline transmission: J:194202
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Modified isoform(s)) Mutation:    Insertion   Mutation details: A neo cassette was inserted into the ATG start codon in the first exon. RT-PCR confirmed the absence of transcripts for isoform a in E13.5 embyos but an increase in isoform b transcripts. (J:194202)

Generation of the Flvcr1tm1Etol allele

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Flvcr1 Mutation:	30 strains or lines available

Original:	J:194202 Chiabrando D, et al., The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation. J Clin Invest. 2012 Dec 3;122(12):4569-79
All:	1 reference(s)