Gene Expression Data
Assay Details
Assay
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Reference:
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J:48134
Grigoriou M, et al., Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development. Development. 1998 Jun;125(11):2063-74
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5473823
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Gene symbol:
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Lhx6
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Gene name:
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LIM homeobox protein 6
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Probe:
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Lhx6 cDNA4
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
not shown E9.5:
embryonic day 9.5
(more )
Specimen
not shown E9.5:
(close )
Genetic Background:
|
Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
3A:
embryonic day 10.5
(more )
Specimen
3A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS17: 1st branchial arch |
Strong |
Regionally restricted |
3A
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High levels of expression restricted to subdomains of the first branchial arch.
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Specimen
3C:
embryonic day 10.5
(more )
Specimen
3C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
|
Not Specified
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Type:
|
whole mount
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Fixation:
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4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: 1st branchial arch mandibular component |
Present |
Regionally restricted |
3C
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Expression in oral (future odontogenic) aspect of mandibular process and part of maxillary process, subdomains bordering the cleft separating the two facial primordia.
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TS17: 1st branchial arch maxillary component |
Present |
Regionally restricted |
3C
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Expression in oral (future odontogenic) aspect of mandibular process and part of maxillary process, subdomains bordering the cleft separating the two facial primordia.
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Specimen
3E:
embryonic day 10.5
(more )
Specimen
3E:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
|
Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
not shown E11.5:
embryonic day 11.5
(more )
Specimen
not shown E11.5:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 11.5
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Sex:
|
Not Specified
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Type:
|
Not Specified
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS19: 1st branchial arch |
Present |
Regionally restricted |
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Authors report expression in a pattern similar to that of the previous stage.
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Specimen
4A:
embryonic day 12.5
(more )
Note: Tooth germ stage.
Specimen
4A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Tooth germ stage.
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Specimen
4C:
embryonic day 13.5
(more )
Note: Tooth bud stage.
Specimen
4C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Tooth bud stage.
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Structure |
Level |
Pattern |
Image |
Note |
TS21: lower jaw mesenchyme |
Present |
Regionally restricted |
4C
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Expression downregulated in most regions of maxillary and mandibular mesenchyme, but maintained and/or upregulated in mesenchyme adjacent to epithelial thickenings constituting the tooth primordia.
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TS21: upper jaw mesenchyme |
Present |
Regionally restricted |
4C
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Expression downregulated in most regions of maxillary and mandibular mesenchyme, but maintained and/or upregulated in mesenchyme adjacent to epithelial thickenings constituting the tooth primordia.
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Specimen
4E:
embryonic day 14.5
(more )
Note: Cap stage.
Specimen
4E:
(close )
Genetic Background:
|
Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Note:
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Cap stage.
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Specimen
5A:
embryonic day 11.5
(more )
Specimen
5A:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS19: telencephalon |
Present |
Regionally restricted |
5A
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Expression in the medial ganglionic eminence, mainly in the subventricular and submantle zones. No expression in the lateral ganglionic eminence.
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Specimen
5B:
embryonic day 13.5
(more )
Specimen
5B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5C:
embryonic day 15.5
(more )
Specimen
5C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
not shown E11.5 (section):
embryonic day 11.5
(more )
Specimen
not shown E11.5 (section):
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS19: forebrain |
Present |
Regionally restricted |
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Domain of expression extends up to a group of cells expressing Fgff8 in the midline of the basal forebrain.
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