Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:86999
Mao D, et al., Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway. Immunity. 2003 Dec;19(6):813-22
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:5473685
|
|
Gene symbol:
|
C3
|
|
Gene name:
|
complement component 3
|
|
Antibody:
|
Anti-C3
|
|
Detection system:
|
Secondary antibody coupled to horseradish peroxidase
|
|
|
Results
|
Specimen
1A:
embryonic day 7.5
(more  )
Specimen
1A:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 7.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
1B:
(close )
|
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Cr1ltm1Hmo/Cr1ltm1Hmo
|
|
Age:
|
embryonic day 7.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS11: trophectoderm |
Present |
Widespread |
1B
|
Expression was extensive.
|
Specimen
1C:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS11: trophectoderm |
Present |
Widespread |
1C
|
Expression was extensive.
|
Specimen
1D:
(close )
|
Genetic Background:
|
involves: 129S/Sv * 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Cfbtm1Hrc/Cfbtm1Hrc
Cr1ltm1Hmo/Cr1ltm1Hmo
|
|
Age:
|
embryonic day 7.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS11: trophectoderm |
Trace |
|
1D
|
No increased C3 deposition was noted in the trophectoderm.
|
Specimen
not shown:
embryonic day 8.5
(more )
Specimen
not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 8.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
not shown:
(close )
|
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Cr1ltm1Hmo/Cr1ltm1Hmo
|
|
Age:
|
embryonic day 8.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
4A:
embryonic day 9.5
(more )
Specimen
4A:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
4B:
(close )
|
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Cr1ltm1Hmo/Cr1ltm1Hmo
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
not shown:
embryonic day 10.5
(more )
Specimen
not shown:
(close )
|
Genetic Background:
|
Not Specified
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
Specimen
not shown:
(close )
|
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
|
|
Mutant Allele(s):
|
Cr1ltm1Hmo/Cr1ltm1Hmo
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Cryosection
|
|
Analysis Tools