Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wnt16tm1Lex
Name:	wingless-type MMTV integration site family, member 16; targeted mutation 1, Lexicon Genetics
MGI ID:	MGI:5467557
Synonyms:	Wnt16-,exon1-3
Gene:	Wnt16  Location: Chr6:22288226-22298521 bp, + strand  Genetic Position: Chr6, 9.22 cM, cytoband A3
Alliance:	Wnt16tm1Lex page

Germline Transmission:	Earliest citation of germline transmission: J:188156
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     A lacZ and floxed neo cassette replaced exons 1, 2 and 3. (J:188156, J:227247)

Generation of the Wnt16tm1Lex allele

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt16 Mutation:	28 strains or lines available

Original:	J:188156 Zheng HF, et al., WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet. 2012 Jul;8(7):e1002745
All:	4 reference(s)