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Gene Expression Data
Assay Details
Assay
Reference: J:12612 Tessarollo L, et al., trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues [published erratum appears in Development 1993 Aug;118(4):following 1384]. Development. 1993 Jun;118(2):463-75
Assay type: RNA in situ
MGI Accession ID: MGI:5464018
Gene symbol: Ntrk3
Gene name: neurotrophic tyrosine kinase, receptor, type 3
Probe: TrkC probe2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen Not shown E7.5: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: neural ectoderm Weak

Specimen 2A/B: embryonic day 9.5 (more )
Note: 12-30 somites.
Structure Level Pattern Image Note
TS15: migrating neural crest Present 2A/B
TS15: nervous system Present 2A/B

Specimen 2C/D: embryonic day 9.5 (more )
Note: 12-30 somites.
Structure Level Pattern Image Note
TS15: dorsal root ganglion Present 2C/D
TS15: migrating neural crest Present 2C/D
TS15: nervous system Present 2C/D
TS15: trunk Present Regionally restricted 2C/D Expression is in regions adjacent to the neural tube and dorsal aorta.

Specimen 2E/F: embryonic day 11.5 (more )
Note: 35 somites.
Structure Level Pattern Image Note
TS19: branchial arch artery Present 2E/F
TS19: diencephalon Present 2E/F
TS19: gonadal mesenchyme Present 2E/F
TS19: hindbrain Present 2E/F
TS19: midbrain Present 2E/F
TS19: midgut Present 2E/F
TS19: neural tube Present 2E/F
TS19: neural tube mantle layer Present 2E/F
TS19: telencephalon Present 2E/F

Specimen 2G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nervous system Present 2G

Specimen 2H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nervous system Present 2H
TS21: trigeminal ganglion Present 2H
TS21: enteric nervous system Present Regionally restricted 2H Expression is in neural-crest-derived cells.

Specimen 2I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nervous system Present 2I
TS21: trigeminal ganglion Present Punctate 2I

Specimen 3C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex intermediate zone Strong 3C
TS25: cortical plate Strong 3C
TS25: dental papilla Present 3C
TS25: dorsal root ganglion Present 3C
TS25: facial ganglion Present 3C
TS25: tongue Present 3C
TS25: vagus ganglion Present 3C
TS25: vestibulo-cochlear ganglion Present 3C
TS25: vibrissa Present 3C
TS25: enteric nervous system Present Regionally restricted 3C Expression is in enteric ganglia.
TS25: telencephalon ventricular layer Weak Regionally restricted 3C
TS25: corpus striatum Present Regionally restricted 3C Expression is in the center.
TS25: thalamus Present Regionally restricted 3C Expression is in thalamic nuclei.
TS25: trigeminal ganglion Present Regionally restricted 3C Expression is in a subset of neurons.

Specimen 4A/B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: caudate-putamen Strong 4A/B
TS25: cortical plate Strong 4A/B
TS25: cerebral cortex intermediate zone Present 4A/B
TS25: telencephalon ventricular layer Weak 4A/B

Specimen 4C/D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical plate Strong 4C/D
TS25: cerebral cortex intermediate zone Present 4C/D
TS25: telencephalon ventricular layer Weak 4C/D

Specimen 4E/F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord mantle layer Present Regionally restricted 4E/F Expression is throughout the dorsal-ventral axis of the mantle layer.
TS23: ventral grey horn Present 4E/F
TS23: spinal cord floor plate Absent 4E/F

Specimen 5A/B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebellum Strong Regionally restricted 5A/B Expression is in the Purkinje cell layer, absent in the external germinal layer.

Specimen 5C/D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebellum Strong Regionally restricted 5C/D Expression is in the Purkinje cell layer, absent in the external germinal layer.

Specimen 5E: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 5E
TS28: cerebellum granule cell layer Strong 5E

Specimen 5F: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 5F
TS28: cerebellum granule cell layer Strong 5F

Specimen 6C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: dorsal root ganglion Present Regionally restricted 6C Expression is in a subset of neurons.

Specimen 7A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: gut mesenchyme Present Regionally restricted 7A Expression is in migratory neural crest cells intercalated within the mesenchyme.
TS21: migrating neural crest Present Regionally restricted 7A Expression is in migratory neural crest cells intercalated within the mesenchyme.

Specimen 7B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: enteric nervous system Present Regionally restricted 7B Expression is in the forming ganglia that appear throughout the muscle and submucosal layers of the intestine.
TS25: intestine Present Regionally restricted 7B Expression is in the forming ganglia that appear throughout the muscle and submucosal layers of the intestine.

Specimen 8A: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: neocortex layer Strong 8A Expression is particularly high in the superficial layers and in the deep layers with reduced expression in the intermediate layers.
TS28: thalamus Present Regionally restricted 8A Expression is in thalamic nuclei.
TS28: dentate gyrus Strong 8A
TS28: hippocampus pyramidal cell layer Strong 8A

Specimen 8B: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Strong 8B
TS28: dentate gyrus Strong 8B
TS28: hippocampus pyramidal cell layer Strong 8B
TS28: thalamus Present Regionally restricted 8B Expression is in thalamic nuclei.

Specimen 8C: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 8C
TS28: hippocampus pyramidal cell layer Strong 8C

Specimen 9A/B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: submandibular gland primordium Present 9A/B

Specimen 9C/D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: trunk mesenchyme Present Regionally restricted 9C/D Expression is in the mesenchyme surrounding mesonephric and urogenital ducts

Specimen 9E/F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: integumental system Strong Regionally restricted 9E/F Expression is in brown adipose tissue dorsal to the cervical spinal cord.

Specimen 9G/H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: adrenal gland Present 9G/H
TS23: renal cortex Present 9G/H

Specimen 9I/J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: arterial system Present Regionally restricted 9I/J Expression is in the subendothelial mesenchyme of arteries throughout the developing embryo.

Specimen Table 1 E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present
TS15: future hindbrain Present
TS15: future midbrain Present
TS15: neural tube Present
TS15: neural crest Present
TS15: arterial system Present Regionally restricted Expression is in aortic arch arteries.

Specimen Table 1 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: acoustic ganglion Present
TS19: diencephalon Present
TS19: dorsal aorta Present
TS19: dorsal root ganglion Present
TS19: facial ganglion Present
TS19: hindbrain Present
TS19: inferior glossopharyngeal ganglion Present
TS19: midbrain Present
TS19: neural tube Present
TS19: superior glossopharyngeal ganglion Present
TS19: superior vagus ganglion Present
TS19: telencephalon Present
TS19: trigeminal ganglion Present
TS19: urogenital sinus Present Regionally restricted Expression is in urogenital mesenchyme.

Specimen Table 1 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: arterial system Present
TS21: cerebellum Present
TS21: corpus striatum Present
TS21: diencephalon Present
TS21: dorsal aorta Present
TS21: dorsal root ganglion Present
TS21: medulla oblongata Present
TS21: neocortex Present
TS21: pons Present
TS21: spinal cord Present
TS21: trigeminal ganglion Present
TS21: vestibulo-cochlear ganglion Present
TS21: telencephalon Present Regionally restricted Expression is basal.
TS21: forebrain Present Regionally restricted Expression is in the hippocampus neo.
TS21: facial nerve Present Regionally restricted Expression is in the facial nucleus.
TS21: sympathetic ganglion Present Regionally restricted Coeliac ganglion.
TS21: urogenital sinus Present Regionally restricted Expression is in urogenital mesenchyme.

Specimen Table 1 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: adrenal gland Present
TS23: aorta Present
TS23: cerebral cortex intermediate zone Present
TS23: corpus striatum Present
TS23: cortical plate Present
TS23: dorsal root ganglion Present
TS23: medulla oblongata Present
TS23: neocortex Present
TS23: pons Present
TS23: spinal cord Present
TS23: submandibular gland primordium Present
TS23: sympathetic ganglion Present
TS23: trigeminal ganglion Present
TS23: vestibulo-cochlear ganglion Present
TS23: vibrissa Present
TS23: cerebellum Present External germinal layer and Purkinje cell layer.
TS23: enteric nervous system Present Regionally restricted Intestinal ganglia.
TS23: arterial system Present Regionally restricted Lung arteries.
TS23: integumental system Present Regionally restricted Cervical brown adipose tissue.
TS23: foot Present Regionally restricted Foot pad.

Specimen Table 1 E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: adrenal gland Present
TS25: aorta Present
TS25: brown fat Present
TS25: cerebral cortex intermediate zone Present
TS25: corpus striatum Present
TS25: cortical plate Present
TS25: dorsal root ganglion Present
TS25: enteric nervous system Present
TS25: foot Present
TS25: medulla oblongata Present
TS25: neocortex Present
TS25: pons Present
TS25: spinal cord Present
TS25: submandibular gland Present
TS25: sympathetic ganglion Present
TS25: trigeminal ganglion Present
TS25: vestibulo-cochlear ganglion Present
TS25: vibrissa Present
TS25: cerebellum Present External germinal layer and Purkinje cell layer.
TS25: arterial system Present Regionally restricted Lung arteries.

Specimen Table 1 P10: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: anterior olfactory nucleus Present
TS28: caudate-putamen Present
TS28: cerebellum Purkinje cell layer Present
TS28: cerebellum granule cell layer Present
TS28: cerebral cortex Present
TS28: fornix Present
TS28: hippocampus Present
TS28: medulla oblongata Present
TS28: thalamus Present Regionally restricted Thalamic nuclei.

Specimen Table 1 P w 6: postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: anterior olfactory nucleus Present
TS28: cerebellum Purkinje cell layer Present
TS28: cerebellum granule cell layer Present
TS28: cerebral cortex Present
TS28: hippocampus Present
TS28: hypothalamus Present
TS28: thalamus Present Regionally restricted Thalamic nuclei.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory