Gene Expression Data
Assay Details
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Assay
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Reference:
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J:32932
Meno C, et al., Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. Nature. 1996 May 9;381(6578):151-5
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5463912
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Gene symbol:
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Lefty1
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Gene name:
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left right determination factor 1
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Results
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Specimen
not shown:
embryonic day 6.0
(more  )
Specimen
not shown:
(close  )
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Genetic Background:
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ICR
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Age:
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embryonic day 6.0
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Sex:
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Not Specified
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Type:
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Not Specified
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Specimen
3a:
embryonic day 6.5
(more )
Specimen
3a:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 6.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS9: primitive streak |
Present |
Regionally restricted |
3a
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Expression was detected in the anterior half of the streak.
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Specimen
3b:
embryonic day 7.0
(more )
Specimen
3b:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS10: primitive streak |
Present |
Regionally restricted |
3b
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Expression was detected along the streak except at the caudal and rostral extremities.
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Specimen
3c:
embryonic day 7.0
(more )
Specimen
3c:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS10: embryo mesoderm |
Present |
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3c
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There was no assymmetry in the expression at this stage.
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Specimen
not shown:
embryonic day 7.5
(more )
Specimen
not shown:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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Not Specified
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Specimen
not shown:
embryonic day 7.75
(more )
Note: Presomite headfold stage.
Specimen
not shown:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 7.75
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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Presomite headfold stage.
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Specimen
3d:
embryonic day 8.0
(more )
Specimen
3d:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: embryo |
Present |
Regionally restricted |
3d
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Expression was highly expressed in 2 regions. Staining in the lateral region extended laterally along the anteroposterior axis. The second region was near the ventral midline. Expression was only on the left side.
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Specimen
3e:
embryonic day 8.0
(more )
Specimen
3e:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: embryo |
Present |
Regionally restricted |
3e
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Expression was highly expressed in 2 regions. Staining in the lateral region extended laterally along the anteroposterior axis. The second region was near the ventral midline.
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Specimen
3f:
embryonic day 8.0
(more )
Specimen
3f:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Specimen
3g:
embryonic day 8.0
(more )
Specimen
3g:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Specimen
3h:
embryonic day 8.0
(more )
Specimen
3h:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Specimen
3i & 3m:
embryonic day 8.0
(more )
Specimen
3i & 3m:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Specimen
3j (middle):
embryonic day 8.0
(more )
Note: Curator's note: Fig. 3 has two panes labeled as 'j'. The data for 3j has been assigned to this specimen based on the pane's position in the figure.
Specimen
3j (middle):
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Note:
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Curator's note: Fig. 3 has two panes labeled as 'j'. The data for 3j has been assigned to this specimen based on the pane's position in the figure.
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Specimen
3k:
embryonic day 8.0
(more )
Specimen
3k:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Specimen
3j (top right):
embryonic day 8.0
(more )
Note: Curator's note: Fig. 3 has two panes labeled as 'j'. The data for 3l has been assigned to this specimen based on the pane's position in the figure.
Specimen
3j (top right):
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Note:
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Curator's note: Fig. 3 has two panes labeled as 'j'. The data for 3l has been assigned to this specimen based on the pane's position in the figure.
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Specimen
not shown:
embryonic day 8.5
(more )
Note: 6-8 somites.
Specimen
not shown:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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Not Specified
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Note:
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6-8 somites.
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Specimen
4a left:
embryonic day 8.0; Dnah11iv/ Dnah11iv
(more )
Note: 3-4 somites.
Specimen
4a left:
(close )
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Genetic Background:
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SI/Col Tyrp1b Dnah11iv/J
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Mutant Allele(s):
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Dnah11iv/Dnah11iv
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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3-4 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: embryo |
Present |
Regionally restricted |
4a left
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In 3/7 homozygous mutant embryos the expression pattern was inverted and found on the right side.
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Specimen
4a right:
embryonic day 8.0; Dnah11iv/ Dnah11iv
(more )
Note: 3-4 somites.
Specimen
4a right:
(close )
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Genetic Background:
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SI/Col Tyrp1b Dnah11iv/J
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Mutant Allele(s):
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Dnah11iv/Dnah11iv
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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3-4 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: embryo |
Present |
Regionally restricted |
4a right
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In 4/7 homozygous mutant embryos the expression was on the left side.
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Specimen
4b:
(close )
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Genetic Background:
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SI/Col Tyrp1b Dnah11iv/J
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Mutant Allele(s):
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Dnah11iv/Dnah11iv
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Note:
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3-4 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: neural plate |
Present |
Regionally restricted |
4b
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In 3/7 homozygous mutant embryos the expression pattern was inverted and found on the right side.
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| TS12: splanchnopleure |
Present |
Regionally restricted |
4b
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In 3/7 homozygous mutant embryos the expression pattern was inverted and found on the right side.
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| TS12: somatopleure |
Present |
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4b
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Ectopic expression in the somatopleure was noted in all homozygous mutant embryos.
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Specimen
4c:
(close )
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Genetic Background:
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SI/Col Tyrp1b Dnah11iv/J
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Mutant Allele(s):
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Dnah11iv/Dnah11iv
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Age:
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embryonic day 8.0
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Age Note:
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Age assigned by curator based on morphological criteria supplied by authors.
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Note:
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3-4 somites.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS12: neural plate |
Present |
Regionally restricted |
4c
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In 4/7 homozygous mutant embryos the expression was on the left side.
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| TS12: splanchnopleure |
Present |
Regionally restricted |
4c
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In 4/7 homozygous mutant embryos the expression was on the left side.
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| TS12: somatopleure |
Present |
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4c
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Ectopic expression in the somatopleure was noted in all homozygous mutant embryos.
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Analysis Tools