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Gene Expression Data
Assay Details
Assay
Reference: J:190997 Medio M, et al., Wnt/beta-catenin signaling and Msx1 promote outgrowth of the maxillary prominences. Front Physiol. 2012;3:375
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5463612
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-PECAM
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen Msx1+/-: embryonic day 12.5; Msx1tm1Bero/Msx1+ (more )
Note: coronal section
Structure Level Pattern Image Note
TS20: fronto-nasal process mesenchyme Present Regionally restricted 4C , 4A Expression in the blood vessels is widely distributed throughout the tissue.
TS20: maxillary process mesenchyme Present Regionally restricted 4C , 4A Expression in the blood vessels is widely distributed throughout the tissue.
TS20: blood vessel Present Widespread 4A , 4C , 4G , 4E The lumen of the expressing vessels is uniformly small.
Specimen Msx1-/-: embryonic day 12.5; Msx1tm1Bero/Msx1tm1Bero (more )
Note: coronal section
Structure Level Pattern Image Note
TS20: fronto-nasal process mesenchyme Present Regionally restricted 4B , 4D Expression in the blood vessels is widely distributed throughout the tissue.
TS20: maxillary process mesenchyme Present Regionally restricted 4B , 4D Expression in the blood vessels is widely distributed throughout the tissue.
TS20: blood vessel Present 4D , 4H , 4B , 4F The lumen of the expressing vessels is larger in the mutants compared to wild type. They are also less dense.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory