Ntn1 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:37125 Serafini T, et al., Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell. 1996 Dec 13;87(6):1001-14
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5461937
Gene symbol:	Ntn1
Gene name:	netrin 1

Reporter:	lacZ
Antibody:	anti-B-galactosidase
Detection system:	Secondary antibody coupled to fluorescein

Results

Specimen 1D: embryonic day 10.5; Ntn1^Gt(ST629)Byg/Ntn1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present		1D

Specimen 1E: embryonic day 10.5; Ntn1^Gt(ST629)Byg/Ntn1^Gt(ST629)Byg (more

)

Structure	Level	Pattern	Image	Note
TS17: neural tube floor plate	Present		1E	Distribution of fusion protein is similar as in wild-type.

Specimen 3D: embryonic day 10.5; Ntn1^Gt(ST629)Byg/Ntn1⁺ (more

)
Note: Double labeled: green - Ntn1; red - Cntn2 (assay MGI:5461912).

Structure	Level	Pattern	Image	Note
TS17: future spinal cord	Present		3D
TS17: neural tube floor plate	Present		3D

Specimen 3E: embryonic day 10.5; Ntn1^Gt(ST629)Byg/Ntn1^Gt(ST629)Byg (more

)
Note: Double labeled: green - Ntn1; red - Cntn2 (assay MGI:5461912).

Structure	Level	Pattern	Image	Note
TS17: future spinal cord	Present		3E	Distribution of fusion protein is similar as in wild-type.
TS17: neural tube floor plate	Present		3E	Distribution of fusion protein is similar as in wild-type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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