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Gene Expression Data
Assay Details
Assay
Reference: J:80765 Romand R, et al., The retinoic acid receptors RARalpha and RARgamma are required for inner ear development. Mech Dev. 2002 Dec;119(2):213-23
Assay type: RNA in situ
MGI Accession ID: MGI:5460882
Gene symbol: Rarb
Gene name: retinoic acid receptor, beta
Probe: mRAR-beta
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: endolymphatic appendage mesenchyme Present Regionally restricted 1B Expression was detected in the mesenchyme around the presumptive endolymphatic duct.
TS17: fronto-nasal process mesenchyme Present 1B
TS17: hindbrain Absent 1B
TS17: otocyst epithelium Absent 1B

Specimen 1E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Regionally restricted 1E Expression was confined to the medio-dorsal side of the otocyst epithelium, mainly in the presumptive vestibular epithelium.
TS20: inner ear mesenchyme Present Regionally restricted 1E Expression was detected in the mesenchyme adjacent to the otocyst epithelium.

Specimen 1G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlea Present Regionally restricted 1G Expression was detected in the mesenchymal tissues of the cochlea. Expression was absent from the cochlear canal.
TS22: cochlear ganglion Absent 1G
TS22: vestibulocochlear nerve cochlear component Absent 1G

Specimen 1J: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlea Present Regionally restricted 1J Expression was detected in mesenchymal tissues such as the modiolus, as well as the Reissner and the basilar membranes.

Specimen 1M: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlea Present Regionally restricted 1M Expression was detected in the basilar membrane. No expression was noted in Kolliker's organ.
TS26: organ of Corti Absent 1M

Specimen 2B: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cochlear duct Absent 2B Expression was not detected in the cochlear canal.

Specimen not shown: postnatal month 3 (more )
Structure Level Pattern Image Note
TS28: inner ear Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory