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Gene Expression Data
Assay Details
Assay
Reference: J:45684 Iwasaki M, et al., Expression of indian hedgehog, bone morphogenetic protein 6 and gli during skeletal morphogenesis. Mech Dev. 1997 Dec;69(1-2):197-202
Assay type: RNA in situ
MGI Accession ID: MGI:5445804
Gene symbol: Bmp6
Gene name: bone morphogenetic protein 6
Probe: Bmp6 cDNA5
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 1I: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: femur cartilage condensation Present Regionally restricted 1I Expression localized to hypertrophic chondrocytes adjacent to ihh-expressing cells.

Specimen 1N: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: forelimb phalanx Present Regionally restricted 1N Expression in hypertrophic chondrocytes adjacent to ihh expression domain in phalanx,

Specimen 1S: postnatal day 8 (more )
Structure Level Pattern Image Note
TS28: long bone epiphyseal plate hypertrophic zone Present 1S Expression in growth plate and epiphyseal hypertrophic chondrocytes.

Specimen not shown: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: long bone epiphyseal plate Absent
TS28: long bone epiphysis Absent

Specimen not shown: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: axial skeleton Absent

Specimen 3D: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: vertebra Present Regionally restricted 3D Expression in hypertrophic chondrocytes in center of vertebral bodies, and in vertebral bodies.
TS24: nucleus pulposus Absent 3D

Specimen 3G: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: basioccipital bone Present 3G

Specimen 3I: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: Meckel's cartilage Present Regionally restricted 3I Expression in proximal mandible and sclerotic ossicles derived from proximal region of Meckel's cartilage.
TS25: mandible Present Regionally restricted 3I Expression in proximal mandible and sclerotic ossicles derived from proximal region of Meckel's cartilage.

Specimen 3K: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: Meckel's cartilage Strong Regionally restricted 3K High expression in distal aspect of Meckel's cartilage and in body of mandible lateral to cartilage rod.
TS25: mandible Strong Regionally restricted 3K High expression in distal aspect of Meckel's cartilage and in body of mandible lateral to cartilage rod.

Specimen 3M: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: nasal bone Present 3M Expression in neural crest-derived intramembranous nasal bones.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory