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Gene Expression Data
Assay Details
Assay
Reference: J:80954 Chapman DL, et al., Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. Nature. 1998 Feb 12;391(6668):695-7
Assay type: RNA in situ
MGI Accession ID: MGI:5445771
Gene symbol: Tcf15
Gene name: transcription factor 15
Probe: paraxis probe6
Probe preparation: Antisense RNA
Results
Specimen normal: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Present Widespread 3c left
TS15: somite Present 3c left Expression is present along the entire rostral-caudal axis.
Specimen Tbx6-mutant: embryonic day 9.5; Tbx6tm1Pa/Tbx6tm1Pa (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Absent 3c right
TS15: somite Present Regionally restricted 3c right Expression is restricted to the most anterior somites. There is no expression in the paraxial "tubes" found in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory