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Gene Expression Data
Assay Details
Assay
Reference: J:25144 Lyons KM, et al., Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. Mech Dev. 1995 Mar;50(1):71-83
Assay type: RNA in situ
MGI Accession ID: MGI:5444663
Gene symbol: Bmp7
Gene name: bone morphogenetic protein 7
Probe: Bmp7 cDNA6
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen Not shown: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: primitive streak Present Regionally restricted Expression is present in the anterior primitive streak and node.

Specimen 1B: embryonic day 7.5 (more )
Note: Headfold stage embryo.
Structure Level Pattern Image Note
TS11: allantois Present 1A/B
TS11: embryo mesoderm Present Regionally restricted 1A/B Expression is present in the axial mesoderm. It is not present other mesodermal derivatives of the primitive streak such as the lateral plate mesoderm underlying the anterior part of the headfold.
TS11: extraembryonic visceral endoderm Weak 1A/B

Specimen 2B: embryonic day 8.5 (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: notochord Present 2A/B
TS13: trunk mesenchyme Present Regionally restricted 2A/B Expression is present in the axial mesoderm.
TS13: embryo endoderm Strong 2A/B
TS13: surface ectoderm Present 2A/B Expression is present in non-neural ectoderm.
TS13: yolk sac Present 2A/B
TS13: somite Absent 2A/B

Specimen 2D: embryonic day 8.5 (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: embryo endoderm Strong 2C/D
TS13: cardiac muscle tissue Present 2C/D Expression is present in myocardial cells of the primitive heart tube.
TS13: somatopleure Present 2C/D
TS13: yolk sac Present 2C/D
TS13: notochord Present 2C/D

Specimen 3B: embryonic day 9.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS15: diencephalon Strong Regionally restricted 3A/B Expression is present in the dorsal part of the diencephalon, with graded expression near the boundary of the dorsal diencephalon and the dorsal mesencephalon. It is also in the ventral diencephalon in the region of the optic chiasma.
TS15: future midbrain Strong Regionally restricted 3A/B Expression is present in part of the ventral mesencephalon.
TS15: future hindbrain Strong Regionally restricted 3A/B Expression is present along the length of the thin roof plate of the myelencephalon.
TS15: notochord Strong 3A/B
TS15: midgut mesenchyme Present Regionally restricted 3A/B
TS15: hindgut Present 3A/B
TS15: foregut Absent 3A/B
TS15: cardiac muscle tissue Present 3A/B
TS15: surface ectoderm Present 3A/B

Specimen Not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted Expression is present in the ventral diencephalon.
TS17: hindbrain roof plate Present Expression is present in the myelencephalon.
TS17: eye Present Expression is present in the optic vesicle.
TS17: otocyst epithelium Present

Specimen 3D: embryonic day 10.5 (more )
Note: transverse section
Structure Level Pattern Image Note
TS17: notochord Present 3C/D
TS17: gut mesenchyme Ambiguous 3C/D Expression has begun to decline to levels barely above background.
TS17: hindlimb bud apical ectodermal ridge Present Widespread 3C/D
TS17: hindlimb bud ectoderm Present Widespread 3C/D
TS17: hindlimb bud mesenchyme Present Widespread 3C/D
TS17: mesonephric tubule Strong Regionally restricted 3C/D Expression is present in the mesonephric duct and tubules.
TS17: nephric duct, mesonephric portion Strong Regionally restricted 3C/D Expression is present in the mesonephric duct and tubules.

Specimen 4B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: limb ectoderm Present Widespread 4A/B
TS15: limb mesenchyme Present Widespread 4A/B

Specimen 4D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present Widespread 4C/D
TS17: limb ectoderm Present Widespread 4C/D
TS17: limb mesenchyme Present Widespread 4C/D

Specimen Not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb interdigital region mesenchyme Present
TS20: vertebral pre-cartilage condensation Present

Specimen Not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: limb interdigital region mesenchyme Present
TS23: pelvic girdle skeleton Present
TS23: scapula Present
TS23: cardiac muscle tissue Present

Specimen 5B: embryonic day 9.0 (more )
Note: transverse section
Structure Level Pattern Image Note
TS14: notochord Present 5A/B
TS14: hindgut diverticulum Present 5A/B Expression is present throughout the definitive endoderm of the hindgut.
TS14: gut mesenchyme Present 5A/B
TS14: embryo Present Regionally restricted 5A/B Expression is present in the ventral furrow.

Specimen 6B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: choroid plexus Present 6A/B Expression is present in the choroid plexus and the meninges.
TS20: rib pre-cartilage condensation Present 6A/B Expression is present in the perichondria.
TS20: cranium Present Regionally restricted 6A/B Expression is present in the scapula.
TS20: axial skeleton Present Regionally restricted 6A/B Expressoin is present in the pelvic girdle.
TS20: mandibular process mesenchyme Present 6A/B
TS20: nasal cavity Present Regionally restricted 6A/B Expression is present in the mesenchyme associated with the nasal epithelium.
TS20: cardiac muscle tissue Present 6A/B
TS20: comma-shaped body Present 6A/B
TS20: metanephros Present Regionally restricted 6A/B Expression is present in the developing comma-shaped and S-shaped bodies.
TS20: lung epithelium Present 6A/B
TS20: pancreas Present Regionally restricted 6A/B Expression is present in the epithelial buds.
TS20: epidermis Present 6A/B Expression is present in the basal layers.
TS20: tongue epithelium Present 6A/B
TS20: dental placode Present Regionally restricted 6A/B Expression is present in the developing tooth buds.

Specimen 6D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: rib cartilage condensation Present 6C/D Expression is present in the perichondria.
TS22: vertebral cartilage condensation Present 6C/D Expression is present in the perichondria.
TS22: vertebral pre-cartilage condensation Present 6C/D
TS22: pelvic girdle skeleton Present 6C/D
TS22: scapula cartilage condensation Present 6C/D
TS22: tooth Present 6C/D Expresson is present in developing tooth buds.
TS22: mandible Present 6C/D
TS22: nasal cavity Present Regionally restricted 6C/D Expression is present in the mesenchyme associated with the nasal epithelium.
TS22: cardiac muscle tissue Present 6C/D
TS22: renal tubule Present Regionally restricted 6C/D Expression is restricted to the active nephrogenic zone.
TS22: lung epithelium Present 6C/D
TS22: pancreas Present 6C/D
TS22: intestine muscularis Present 6C/D Expression is present in the muscularis mucosae.
TS22: epidermis Present 6C/D Expression is present in the basal layer.
TS22: vibrissa epidermal component Present 6C/D

Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: inner ear epithelium Present Expression persists within the otic vesicle epithelium through at least E14.5.
TS22: limb cartilage condensation Weak Regionally restricted Expression is present within chondrocytes in developing limb bones.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory