About   Help   FAQ
Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 5, Jeremy Nathans
MGI ID: MGI:5443817
Synonyms: CAG-Sun1sfGFP, R26-CAG-LSL-Sun1-sfGFP-Myc, SUN1-2xsfGFP-6xMYC, Sun1LsL, Sun1-LsL
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:243557
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat expresses 1 gene
 
Mutation detailsA targeting vector containing (from 5' to 3') a CAG promoter, a loxP site flanked STOP cassette, the mouse Sun1 cDNA fused with 2 copies of the superfolder GFP (sfGFP) green fluorescent protein gene and 6 copies of the Myc tag, and an FRT site flanked neomycin resistance gene cassette was inserted into the locus. Removal of the floxed stop cassette is required to achieve expression. (J:243557)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 7 assay results
3 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:243557 Mo A, et al., Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain. Neuron. 2015 Jun 17;86(6):1369-84
All:  69 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory