Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 5, Jeremy Nathans |
MGI ID: |
MGI:5443817 |
Synonyms: |
CAG-Sun1sfGFP, R26-CAG-LSL-Sun1-sfGFP-Myc, SUN1-2xsfGFP-6xMYC, Sun1LsL, Sun1-LsL |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat page
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Germline Transmission: |
Earliest citation of germline transmission:
J:243557
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence, Reporter) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat expresses
1 gene
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Mutation details: A targeting vector containing (from 5' to 3') a CAG promoter, a loxP site flanked STOP cassette, the mouse Sun1 cDNA fused with 2 copies of the superfolder GFP (sfGFP) green fluorescent protein gene and 6 copies of the Myc tag, and an FRT site flanked neomycin resistance gene cassette was inserted into the locus. Removal of the floxed stop cassette is required to achieve expression.
(J:243557)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:243557 Mo A, et al., Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain. Neuron. 2015 Jun 17;86(6):1369-84 |
All: |
69 reference(s) |
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