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Gene Expression Data
Assay Details
Assay
Reference: J:33753 Teesalu T, et al., Embryo implantation in mouse: fetomaternal coordination in the pattern of expression of uPA, uPAR, PAI-1 and alpha 2MR/LRP genes. Mech Dev. 1996 May;56(1-2):103-16
Assay type: RNA in situ
MGI Accession ID: MGI:5440077
Gene symbol: Serpine1
Gene name: serine (or cysteine) peptidase inhibitor, clade E, member 1
Probe: PAI-l cDNA2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1C: postnatal adult (more )
Note: This is a sample from a pregnant mouse at dpc 5.5.
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 1C Abundant expression throughout the area of primary decidual reaction, centered around the implantation site. No expression was seen in the peripheral decidua.

Specimen 1H embryo: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: parietal endoderm Present 1H

Specimen 1H maternal: postnatal adult (more )
Note: This is a sample from a pregnant mouse at dpc 6.5.
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 1H In the antimesometrial pole, expression was in a cup-shaped region in the secondary decidual zone. In the mesometrial pole, labeled cells appeared to radiate from the mesometrial chamber into neighboring areas.

Specimen 1M embryo: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: parietal endoderm Present 1M Expression is the same as in E6.5 embryos.

Specimen 1M maternal: postnatal adult (more )
Note: This is a sample from a pregnant mouse at dpc 7.5.
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 1M Expression is the same as in E6.5 embryos, except that the meso- and antimesometrial expression domains had become clearly distinguishable.

Specimen 1R embryo: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trophoblast giant cell Strong Regionally restricted 1R Expressed in the trophoblast giant cells surrounding the embryonic cavity and the area of placenta formation.
TS13: spongiotrophoblast Absent 1R

Specimen 1R maternal: postnatal adult (more )
Note: This is a sample from a pregnant mouse at dpc 8.5.
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 1R Expressed in decidual cells adjacent to the ectoplacental cone. In the area of placenta formation, expression was in the decidual tissue neighboring trophoblast giant cells.

Specimen 1W embryo: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: trophectoderm Present 1W

Specimen 1W maternal: postnatal adult (more )
Note: This is a sample from a pregnant mouse at dpc 9.5.
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 1W Expressed in decidua vascularis cells.

Specimen 2C: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: cytotrophoblast Absent 2C No expression in ectoplacental cone trophoblast cells.
TS11: syncytiotrophoblast Absent 2C No expression in ectoplacental cone trophoblast cells.

Specimen 2F: postnatal adult (more )
Note: This is a sample from a pregnant mouse at dpc 8.5.
Structure Level Pattern Image Note
TS28: decidua Strong Regionally restricted 2F Expressed in decidual cells adjacent to the ectoplacental cone.

Specimen 2I: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: trophoblast giant cell Strong Regionally restricted 2I Expressed in the trophoblast giant cells surrounding the embryonic cavity.

Specimen 9B embryo: embryonic day 7.5; Plautm1Mlg/Plautm1Mlg (more )
Structure Level Pattern Image Note
TS11: cytotrophoblast Absent 9B No expression in ectoplacental cone trophoblast cells. Expression in this mutant is the same as in wild-type embryos.
TS11: syncytiotrophoblast Absent 9B No expression in ectoplacental cone trophoblast cells. Expression in this mutant is the same as in wild-type embryos.

Specimen 9B maternal: postnatal adult; Plautm1Mlg/Plautm1Mlg (more )
Note: This is a sample from a pregnant mouse at dpc 7.5.
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted 9B Expression in this mutant is the same as in wild-type embryos.
TS28: endometrium Present Regionally restricted 9B Expression in this mutant is the same as in wild-type embryos.

Specimen not shown embryo: embryonic day 8.5; Plautm1Mlg/Plautm1Mlg (more )
Structure Level Pattern Image Note
TS13: trophoblast giant cell Present Regionally restricted Expressed in the trophoblast giant cells surrounding the embryonic cavity and the area of placenta formation. Expression in this mutant is the same as in wild-type embryos.

Specimen not shown maternal: postnatal adult; Plautm1Mlg/Plautm1Mlg (more )
Note: This is a sample from a pregnant mouse at dpc 8.5.
Structure Level Pattern Image Note
TS28: decidua Present Regionally restricted Expressed in decidual cells adjacent to the ectoplacental cone. In the area of placenta formation, expression was in the decidual tissue neighboring trophoblast giant cells. Expression in this mutant is the same as in wild-type embryos.

Specimen not shown: postnatal adult (more )
Note: This is a sample from a non-pregnant mouse.
Structure Level Pattern Image Note
TS28: uterus Absent No expression in non-pregnant uterus.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory