Gene Expression Data
Assay Details
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Assay
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Reference:
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J:70830
Zelzer E, et al., Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. Mech Dev. 2001 Aug;106(1-2):97-106
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5439892
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Gene symbol:
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Runx2
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Gene name:
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runt related transcription factor 2
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Reporter:
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lacZ
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Direct Detection
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Assay notes:
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The fix was 0.2% paraformaldehyde.
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Results
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Specimen
5C:
postnatal newborn; Runx2tm1Mjo/Runx2 +
(more  )
Specimen
5C:
(close  )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Runx2tm1Mjo/Runx2+
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: tibia |
Present |
Regionally restricted |
5C
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Expression was detected in the periosteum of the shaft, in hypertrophic cartilage of the growth plate and within the trabecular bone. There was no staining at or near the articular region.
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Specimen
5D:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Runx2tm1Mjo/Runx2tm1Mjo
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: tibia |
Strong |
Regionally restricted |
5D
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Expression was detected throughout most of the cartilaginous tibia, including the perichondrium, with the exception of the articular regions.
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Analysis Tools
