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Gene Expression Data
Assay Details
Assay
Reference: J:70830 Zelzer E, et al., Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2. Mech Dev. 2001 Aug;106(1-2):97-106
Assay type: RNA in situ
MGI Accession ID: MGI:5439842
Gene symbol: Vegfa
Gene name: vascular endothelial growth factor A
Probe: VEGF probe8
Probe preparation: Antisense labelled with P33 RNA
Results
Specimen 2A/a: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: fibula Present Regionally restricted 2A/a Expression was detected in the hypertrophic zone in a broad domain that includes most of the diaphysis.
TS23: tibia Present Regionally restricted 2A/a Expression was detected in the hypertrophic zone in a broad domain that includes most of the diaphysis.

Specimen 2B/b: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: femur Present Regionally restricted 2B/b Expression was detected in the hypertrophic zones of the growth plates at both ends of the growing bone.
TS25: tibia Present Regionally restricted 2B/b Expression was detected in the hypertrophic zones of the growth plates at both ends of the growing bone.

Specimen 2C/c: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: vertebra Present Regionally restricted 2C/c Expression was detected in the hypertrophic zone.

Specimen 2D/d: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: metatarsus Present Regionally restricted 2D/d Expression was detected in the hypertrophic zone.

Specimen 2E/e: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: rib Present Regionally restricted 2E/e Expression was detected in the hypertrophic zone.

Specimen 3A/a: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: fibula Present Regionally restricted 3A/a Expression was detected in the hypertrophic zones.
TS23: tibia Present Regionally restricted 3A/a Expression was detected in the hypertrophic zones.

Specimen 3B/b: embryonic day 17.5; Runx2tm1Mjo/Runx2tm1Mjo (more )
Structure Level Pattern Image Note
TS25: tibia Absent 3B/b Only background labeling was noted.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory