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Gene Expression Data
Assay Details
Assay
Reference: J:51596 Lu MF, et al., prx-1 functions cooperatively with another paired-related homeobox gene, prx-2, to maintain cell fates within the craniofacial mesenchyme. Development. 1999 Feb;126(3):495-504
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5436562
Gene symbol: Prrx1
Gene name: paired related homeobox 1
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 9.5; Prrx1tm1Jfm/Prrx1+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch maxillary component Present 2A Expression is present in the forming maxillary process.
TS15: 1st branchial arch mandibular component Present Non-Uniform 2A Expression is present in the forming mandibular process. Expression is highest at the distal end of the process.
TS15: 1st branchial arch Present Regionally restricted 2A Expression is present within cells ventral to the eye that will contribute to the proximal components of the first branchial arch skeleton.

Specimen 2B: embryonic day 9.5; Prrx1tm1Jfm/Prrx1+ (more )
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Present 2B

Specimen 2C: embryonic day 10.0; Prrx1tm1Jfm/Prrx1+ (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch maxillary component Present 2C Expression is present in the forming maxillary process.
TS16: 1st branchial arch mandibular component Present 2C Expression is present in the forming mandibular process.

Specimen 2D: embryonic day 10.0; Prrx1tm1Jfm/Prrx1+ (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch maxillary component Present 2D Expression is present in the forming maxillary process.
TS16: 1st branchial arch mandibular component Present 2D Expression is present in the forming mandibular process.
TS16: ear Present 2D Expression is present in cells surrounding the first branchial groove that will give rise to ear structures, such as the external acoustic meatus and external ear structures.

Specimen 2E: embryonic day 11.5; Prrx1tm1Jfm/Prrx1+ (more )
Structure Level Pattern Image Note
TS19: mandibular process Strong 2E
TS19: maxillary process Strong 2E
TS19: fronto-nasal process Present 2E

Specimen 2F: embryonic day 12.5; Prrx1tm1Jfm/Prrx1+ (more )
Structure Level Pattern Image Note
TS20: mandibular process Present 2F
TS20: maxillary process Present 2F
TS20: outer ear Present 2F
TS20: cranium Present 2F Expression is present in cells that prefigure the dermal bones at the lateral aspect of the head, such as the squamosal and other first arch derivatives.

Specimen Not shown: embryonic day 10.5; Prrx1tm1Jfm/Prrx1+ (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch Present

Specimen Not shown: embryonic day 10.5; Prrx1tm1Jfm/Prrx1tm1Tex (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch Present Expression in the mutant is similar to that seen in wild type.

Specimen 3A: embryonic day 11.5; Prrx1tm1Jfm/Prrx1+ (more )
Structure Level Pattern Image Note
TS19: skeleton Present Regionally restricted 3A Expression is present in cells fated to give rise to the dermal bones of the lateral skull.
TS19: mandibular process Present 3A
TS19: maxillary process Present 3A

Specimen 3B: embryonic day 11.5; Prrx1tm1Jfm/Prrx1tm1Tex (more )
Structure Level Pattern Image Note
TS19: skeleton Present Regionally restricted 3B As in wild type, expression is present in cells fated to give rise to the dermal bones of the lateral skull.
TS19: mandibular process Present 3B
TS19: maxillary process Present 3B

Specimen 3C: embryonic day 12.5; Prrx1tm1Jfm/Prrx1+ (more )
Structure Level Pattern Image Note
TS20: cranium Present 3C Expression is present in cells that are forming membrane bones.
TS20: mandibular process Present 3C
TS20: maxillary process Present 3C

Specimen 3D: embryonic day 12.5; Prrx1tm1Jfm/Prrx1tm1Tex (more )
Structure Level Pattern Image Note
TS20: cranium Absent 3D In the mutant, expression is lost from cells that will form the lateral skull bones, such as the squamosal and other first arch derivatives.
TS20: mandibular process Present 3D
TS20: maxillary process Present 3D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory