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Gene Expression Data
Assay Details
Assay
Reference: J:87411 Burns RC, et al., Requirement for fibroblast growth factor 10 or fibroblast growth factor receptor 2-IIIb signaling for cecal development in mouse. Dev Biol. 2004 Jan 1;265(1):61-74
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5435229
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: Anti-smooth muscle alpha-Actin (clone 1A4)
Detection system: Secondary antibody coupled to Cy3
Assay notes: Tissue was fixed in methacarn solution.
Results
Specimen 4E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: gut Present 4E Expression proceeds from proximal to distal from the mesenteric side of the bowel wall to the anti-mesenteric side.
TS21: midgut Present 4E Expression in the cecum lags behind that of the large intestine.
TS21: hindgut Present 4E Expression is present in the large intestine.

Specimen 4F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: gut Present Non-Uniform 4F Expression proceeds from proximal to distal from the mesenteric side of the bowel wall to the anti-mesenteric side.
TS22: midgut Present 4F Expression in the cecum has increased in size.

Specimen Not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: small intestine Present Regionally restricted Expression is present in two thin, distinct layers on the outermost portion of the bowel wall.
TS26: large intestine Present Regionally restricted Expression is present in two thin, distinct layers on the outermost portion of the bowel wall. This includes expression in the cecum.

Specimen 4G: embryonic day 14.5; Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn (more )
Structure Level Pattern Image Note
TS22: midgut Present 4G Expression within the small intestine is equivalent to that seen in wild type. However, the mesenchymal cecal remnant does not express.
TS22: hindgut Present 4G Expression within the large intestine is equivalent to that seen in wild type.

Specimen Not shown: embryonic day 14.5; Fgf10tm1Ska/Fgf10tm1Ska (more )
Structure Level Pattern Image Note
TS22: midgut Present Expression within the small intestine is equivalent to that seen in wild type. However, the mesenchymal cecal remnant does not express.
TS22: hindgut Present Expression within the large intestine is equivalent to that seen in wild type.

Specimen 4H: embryonic day 18.5; Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn (more )
Structure Level Pattern Image Note
TS26: small intestine Present 4H Expression within the small intestine is equivalent to that seen in wild type.
TS26: large intestine Present 4H Expression within the large intestine is equivalent to that seen in wild type. However, the mesenchymal cecal remnant does not express.

Specimen Not shown: embryonic day 18.5; Fgf10tm1Ska/Fgf10tm1Ska (more )
Structure Level Pattern Image Note
TS26: small intestine Present Expression within the large and small intestine is equivalent to that seen in wild type.
TS26: large intestine Present Expression within the large intestine is equivalent to that seen in wild type. However, the mesenchymal cecal remnant does not express.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory