Gene Expression Data
Assay Details
Assay
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Reference:
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J:87411
Burns RC, et al., Requirement for fibroblast growth factor 10 or fibroblast growth factor receptor 2-IIIb signaling for cecal development in mouse. Dev Biol. 2004 Jan 1;265(1):61-74
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5435229
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Gene symbol:
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Acta2
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Gene name:
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actin alpha 2, smooth muscle, aorta
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Results
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Specimen
4E:
embryonic day 13.5
(more )
Specimen
4E:
(close )
Genetic Background:
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C57BL/6
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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Structure |
Level |
Pattern |
Image |
Note |
TS21: gut |
Present |
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4E
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Expression proceeds from proximal to distal from the mesenteric side of the bowel wall to the anti-mesenteric side.
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TS21: midgut |
Present |
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4E
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Expression in the cecum lags behind that of the large intestine.
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TS21: hindgut |
Present |
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4E
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Expression is present in the large intestine.
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Specimen
4F:
embryonic day 14.5
(more )
Specimen
4F:
(close )
Genetic Background:
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C57BL/6
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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Structure |
Level |
Pattern |
Image |
Note |
TS22: gut |
Present |
Non-Uniform |
4F
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Expression proceeds from proximal to distal from the mesenteric side of the bowel wall to the anti-mesenteric side.
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TS22: midgut |
Present |
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4F
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Expression in the cecum has increased in size.
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Specimen
Not shown:
embryonic day 18.5
(more )
Specimen
Not shown:
(close )
Genetic Background:
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C57BL/6
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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Structure |
Level |
Pattern |
Image |
Note |
TS26: small intestine |
Present |
Regionally restricted |
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Expression is present in two thin, distinct layers on the outermost portion of the bowel wall.
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TS26: large intestine |
Present |
Regionally restricted |
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Expression is present in two thin, distinct layers on the outermost portion of the bowel wall. This includes expression in the cecum.
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Specimen
4G:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midgut |
Present |
|
4G
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Expression within the small intestine is equivalent to that seen in wild type. However, the mesenchymal cecal remnant does not express.
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TS22: hindgut |
Present |
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4G
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Expression within the large intestine is equivalent to that seen in wild type.
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Specimen
Not shown:
(close )
Genetic Background:
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involves: C57BL/6 * CBA
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Mutant Allele(s):
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Fgf10tm1Ska/Fgf10tm1Ska
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
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Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midgut |
Present |
|
|
Expression within the small intestine is equivalent to that seen in wild type. However, the mesenchymal cecal remnant does not express.
|
TS22: hindgut |
Present |
|
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Expression within the large intestine is equivalent to that seen in wild type.
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Specimen
4H:
(close )
Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn
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Age:
|
embryonic day 18.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
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Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: small intestine |
Present |
|
4H
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Expression within the small intestine is equivalent to that seen in wild type.
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TS26: large intestine |
Present |
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4H
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Expression within the large intestine is equivalent to that seen in wild type. However, the mesenchymal cecal remnant does not express.
|
Specimen
Not shown:
(close )
Genetic Background:
|
involves: C57BL/6 * CBA
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Mutant Allele(s):
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Fgf10tm1Ska/Fgf10tm1Ska
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Age:
|
embryonic day 18.5
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Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
|
Other - See Notes
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: small intestine |
Present |
|
|
Expression within the large and small intestine is equivalent to that seen in wild type.
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TS26: large intestine |
Present |
|
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Expression within the large intestine is equivalent to that seen in wild type. However, the mesenchymal cecal remnant does not express.
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