Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Prrx1-FUS/DDIT3)1Mete
Name:	transgene insertion 1, Melissa Terry
MGI ID:	MGI:5428676
Synonyms:	Prx1-TLS:CHOP, pTC, Tg(Prrx1-TLS/CHOP)1Mete
Transgene:	Tg(Prrx1-FUS/DDIT3)1Mete  Location: unknown
Alliance:	Tg(Prrx1-FUS/DDIT3)1Mete page

Strain of Origin:

(C57BL/6 x CBA)F2

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(Prrx1-FUS/DDIT3)1Mete expresses 2 genes Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human DDIT3 (1649) Ddit3  (MGI:109247) human FUS (2521) Fus  (MGI:1353633)   Mutation details: The mouse promoter drives mesenchyme-specific expression of a human cDNA encoding the fusion of FUS and DDIT3 (TLS:CHOP; type II). The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:184491)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:184491 Charytonowicz E, et al., PPARgamma agonists enhance ET-743-induced adipogenic differentiation in a transgenic mouse model of myxoid round cell liposarcoma. J Clin Invest. 2012 Mar 1;122(3):886-98
All:	1 reference(s)