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Gene Expression Data
Assay Details
Assay
Reference: J:86943 Lauren J, et al., Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems. Mol Cell Neurosci. 2003 Nov;24(3):581-94
Assay type: RNA in situ
MGI Accession ID: MGI:5316851
Gene symbol: Rtn4rl2
Gene name: reticulon 4 receptor-like 2
Probe: NGRL3 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Strong 4C
TS21: inferior glossopharyngeal ganglion Strong 4C
TS21: inferior vagus ganglion Strong 4C
TS21: peripheral nervous system Strong 4C
TS21: trigeminal ganglion Strong 4C
TS21: vestibulo-cochlear ganglion Strong 4C
TS21: cortical plate Strong 4C
TS21: brainstem Weak 4C
TS21: spinal cord Absent 4C
Specimen 4H,I: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: spinal cord Absent 4I , 4H
TS27: dorsal root ganglion Strong 4H , 4I
Specimen 5G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Strong 5G
TS28: anterior olfactory nucleus Strong 5G
TS28: cortical layer II Strong 5G
TS28: cortical layer III Strong 5G
TS28: cortical layer IV Strong 5G
TS28: cortical layer V Strong 5G
TS28: cortical layer VI Strong 5G
TS28: habenula Strong 5G
TS28: hippocampal formation Strong 5G
TS28: main olfactory bulb mitral cell layer Strong 5G
TS28: midbrain Present 5G
TS28: brainstem Present Widespread 5G
TS28: hypothalamus Absent 5G
TS28: cerebellum Absent 5G
Specimen 5H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong Regionally restricted 5H
TS28: cortical layer III Strong Regionally restricted 5H
TS28: cortical layer IV Strong Regionally restricted 5H
TS28: cortical layer V Strong Regionally restricted 5H
TS28: cortical layer VI Strong Regionally restricted 5H
TS28: caudate-putamen Absent 5H
TS28: lateral septal nucleus Absent 5H
Specimen 5I: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer II Strong 5I
TS28: cortical layer III Strong 5I
TS28: cortical layer IV Strong 5I
TS28: cortical layer V Strong 5I
TS28: cortical layer VI Strong 5I
TS28: hippocampal formation Strong 5I
TS28: thalamus Absent 5I There is a discrepancy between Table 1 and the text; the table states there is weak expression in nuclei.
Specimen 6O: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Absent 6O
Specimen 6P: postnatal adult (more )
Structure Level Pattern Image Note
TS28: anterior olfactory nucleus Present 6P
TS28: cerebral cortex Present 6P
TS28: main olfactory bulb mitral cell layer Present 6P
Specimen 6Q: postnatal adult (more )
Structure Level Pattern Image Note
TS28: spinal cord dorsal horn Absent 6Q
Specimen 6R,S,T: postnatal adult (more )
Note: (R,S) Brightfield/dark field pair. (T) is a higher magnification of (S).
Structure Level Pattern Image Note
TS28: corpus callosum Present 6R , 6S , 6T
TS28: cortical layer III Present 6R , 6S , 6T
TS28: cortical layer IV Present 6R , 6S , 6T
TS28: cortical layer V Present 6R , 6S , 6T
TS28: cortical layer VI Present 6R , 6S , 6T
Specimen 6U: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Strong 6U
Specimen Table 1: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA1 pyramidal cell layer Strong
TS28: amygdala Strong
TS28: cortical layer II Strong
TS28: cortical layer III Strong
TS28: cortical layer IV Strong
TS28: cortical layer V Strong
TS28: cortical layer VI Strong
TS28: dentate gyrus granule cell layer Strong
TS28: medial habenular nucleus Strong
TS28: piriform cortex Strong
TS28: trigeminal V mesencephalic nucleus Strong
TS28: hippocampus CA2 Strong Regionally restricted Expression is in pyramidal cell layers.
TS28: hippocampus CA3 Strong Regionally restricted Expression is in pyramidal cell layers.
TS28: anterior olfactory nucleus Moderate
TS28: dorsal root ganglion Moderate
TS28: inferior olivary nucleus Moderate
TS28: locus coeruleus Moderate
TS28: nucleus of trapezoid body Moderate
TS28: septofimbrial nucleus Moderate
TS28: trigeminal ganglion Moderate
TS28: telencephalon Moderate Regionally restricted Expression is in periglomerular cells and the mitral cell layer and is absent in the internal granular layer.
TS28: brainstem Moderate Regionally restricted Expression is in the lateral lemniscus.
TS28: thalamus Weak Regionally restricted Expression is in most nuclei.
TS28: cochlear nucleus Weak
TS28: gigantocellular reticular nucleus Weak
TS28: spinal vestibular nucleus Weak
TS28: arcuate nucleus Absent
TS28: caudate-putamen Absent
TS28: cerebellum Purkinje cell layer Absent
TS28: cerebellum granule cell layer Absent
TS28: choroid plexus Absent
TS28: cuneate nucleus Absent
TS28: globus pallidus Absent
TS28: inferior colliculus Absent
TS28: interpeduncular nucleus Absent
TS28: lateral septal complex Absent
TS28: pallidum Absent
TS28: pontine nucleus Absent
TS28: red nucleus Absent
TS28: reticular tegmental nucleus Absent
TS28: spinal cord dorsal horn Absent
TS28: spinal cord ventral horn Absent
TS28: substantia nigra Absent
TS28: superior colliculus Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory