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Gene Expression Data
Assay Details
Assay
Reference: J:129949 Cui CY, et al., Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5315170
Gene symbol: Flg
Gene name: filaggrin
Antibody: Anti-Filaggrin
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2 WT E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: epidermis Present Regionally restricted 2_Filaggrin WT E16.5 Expression was detected in the keratohyalin granules.
Specimen 2 LTbeta-/- E16.5: embryonic day 16.5; Ltbtm1Kpf/Ltbtm1Kpf (more )
Structure Level Pattern Image Note
TS24: epidermis Present Regionally restricted 2_Filaggrin LT beta-/- E16.5 Expression was elevated at E16.5, staining strongly from the middle squamous layer to the horny layer.
Specimen 2 WT E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epidermis Present Regionally restricted 2_Filaggrin WT E18.5 Expression was detected in the keratohyalin granules.
Specimen 2 LTbeta-/- E18.5: embryonic day 18.5; Ltbtm1Kpf/Ltbtm1Kpf (more )
Structure Level Pattern Image Note
TS26: epidermis Present Regionally restricted 2_Filaggrin LT beta-/- E18.5 Expression was elevated in the mutant compared to wild type, though not as abundantly as at E16.5.
Specimen 2 WT p5: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 2_Filaggrin WT P5 Expression was detected in the keratohyalin granules.
Specimen 2 LTbeta-/- p5: postnatal day 5; Ltbtm1Kpf/Ltbtm1Kpf (more )
Structure Level Pattern Image Note
TS28: epidermis Present Regionally restricted 2_Filaggrin LT beta-/- P5 Expression was elevated in the mutant compared to wild type, though not as abundantly as at E16.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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