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Mir210tm1Mtm
Targeted Allele Detail
Summary
Symbol: Mir210tm1Mtm
Name: microRNA 210; targeted mutation 1, Michael McManus
MGI ID: MGI:5314656
Gene: Mir210  Location: Chr7:140801297-140801406 bp, - strand  Genetic Position: Chr7, 86.52 cM
Alliance: Mir210tm1Mtm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181752
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert an FRT site followed by a lacZ gene, a loxP site, a neomycin cassette, a second FRT site and a second loxP site (FRT-lacZ-loxP-Neo-FRT-loxP) upstream of the microRNA stem loop and a third loxP site immediately downstream of the microRNA stem loop. (J:181752)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mir210 Mutation:  7 strains or lines available
References
Original:  J:181752 Park CY, et al., A resource for the conditional ablation of microRNAs in the mouse. Cell Rep. 2012;1(4):385-91
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory