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Adamts18tm1Zdl
Targeted Allele Detail
Summary
Symbol: Adamts18tm1Zdl
Name: ADAM metallopeptidase with thrombospondin type 1 motif 18; targeted mutation 1, Zongdong Li
MGI ID: MGI:5308778
Synonyms: ADAMTS-18loxP
Gene: Adamts18  Location: Chr8:114423758-114575370 bp, - strand  Genetic Position: Chr8, 59.65 cM
Alliance: Adamts18tm1Zdl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:181091
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a loxP site upstream of exon 5, followed by a frt-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 6 of the a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 (Adamts18) gene. (J:181091)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adamts18 Mutation:  65 strains or lines available
References
Original:  J:181091 Li Z, Direct Data Submission 2012/03/08. MGI Direct Data Submission. 2012;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory