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Gene Expression Data
Assay Details
Assay
Reference: J:79853 Liu C, et al., Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development. 2002 Nov;129(21):5081-91
Assay type: RNA in situ
MGI Accession ID: MGI:5299917
Gene symbol: Pitx2
Gene name: paired-like homeodomain transcription factor 2
Probe: Pitx2c probe3
Probe preparation: Antisense RNA
Results
Specimen 1A: embryonic day 9.5 (more )
Note: Right view of embryo.
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 1A Expression is in the left branchial arch mesoderm.
Specimen 1B: embryonic day 9.5 (more )
Note: Left view of embryo.
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 1B Expression is in the left branchial arch mesoderm.
TS15: mesenchyme derived from splanchnopleure Present Regionally restricted 1B Expression is at the level of and just caudal to the outflow tract.
Specimen 1C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 1C Expression is in the left branchial arch mesoderm.
TS15: mesenchyme derived from splanchnopleure Present Regionally restricted 1C Expression in left splanchnic mesoderm was continuous with expression in left aortic sac mesothelium and outflow tract myocardium.
TS15: outflow tract Present Regionally restricted 1C Expression in left splanchnic mesoderm was continuous with expression in left aortic sac mesothelium and outflow tract myocardium.
Specimen 1D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 1D Expression is in the left branchial arch mesoderm.
TS15: mesenchyme derived from splanchnopleure Present Regionally restricted 1D Expression in left splanchnic mesoderm was continuous with expression in left aortic sac mesothelium and outflow tract myocardium.
TS15: outflow tract Present Regionally restricted 1D Expression in left splanchnic mesoderm was continuous with expression in left aortic sac mesothelium and outflow tract myocardium.
Specimen 1E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 1E Expression is in the left branchial arch mesoderm.
TS15: mesenchyme derived from splanchnopleure Present Regionally restricted 1E Expression in left splanchnic mesoderm was continuous with expression in left aortic sac mesothelium and outflow tract myocardium.
TS15: outflow tract Present Regionally restricted 1E Expression in left splanchnic mesoderm was continuous with expression in left aortic sac mesothelium and outflow tract myocardium.
Specimen 1F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 1F Expression is in left branchial arch mesoderm near junction of the aortic sac with the branchial arch artery.
TS15: mesenchyme derived from splanchnopleure Present Regionally restricted 1F Expression in left splanchnic mesoderm was continuous with expression in left aortic sac mesothelium and outflow tract myocardium.
TS15: outflow tract Present Regionally restricted 1F Expression in left splanchnic mesoderm was continuous with expression in left aortic sac mesothelium and outflow tract myocardium.
Specimen 1G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present Regionally restricted 1G Expression is in dorsal branchial arch mesoderm in proximity to forming branchial arch arteries.
Specimen 1H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch mesenchyme Present Regionally restricted 1H Expression is ventral.
TS17: trunk mesenchyme Present Regionally restricted 1H Expression is in splanchnic mesoderm that is continuous with expression in left branchial arch.
Specimen 1I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch mesenchyme Present Regionally restricted 1I Expression is ventral with less abundant dorsal expression.
TS17: trunk mesenchyme Present Regionally restricted 1I Expression is in splanchnic mesoderm that is continuous with expression in left branchial arch.
Specimen 1J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: common atrial chamber left part Present 1J
TS17: dorsal mesocardium Present 1J
Specimen 1K: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal mesocardium Present 1K
TS17: interatrial septum Present 1K
Specimen 1L: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: common atrial chamber left part Present 1L
TS17: dorsal mesocardium Present 1L Left dorsal mesocardium.
Specimen 1M: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: primitive ventricle cardiac muscle Present 1M
TS17: primitive ventricle Present Regionally restricted 1M Expression is in right ventricular and interventricular myocardium.
Specimen 6D: embryonic day 12.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pitx2tm4(cre)Jfm/Pitx2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: heart Present 6D
Specimen 6F: embryonic day 14.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pitx2tm4(cre)Jfm/Pitx2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: heart Absent 6F
Specimen 6H: embryonic day 16.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pitx2tm4(cre)Jfm/Pitx2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: heart Absent 6H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory