Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dppa2tm1.1Yam
Name:	developmental pluripotency associated 2; targeted mutation 1.1, Shinya Yamanaka
MGI ID:	MGI:5298643
Synonyms:	15-2-
Gene:	Dppa2  Location: Chr16:48130637-48139876 bp, + strand  Genetic Position: Chr16, 30.75 cM
Alliance:	Dppa2tm1.1Yam page

Germline Transmission:	Earliest citation of germline transmission: J:178324
Parent Cell Line:	RF8 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: An FRT site was inserted into intron 1 and an FRT flanked hyg cassette site was inserted after the last exon via homologous recombination. This allele was originally created in tandem with Dppa4tm1Yam. These alleles are in cis to each other. Flp mediated recombination removed the hyg cassette and the FRT flanked region. (J:178324)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dppa2 Mutation:	27 strains or lines available

Original:	J:178324 Nakamura T, et al., Essential roles of ECAT15-2/Dppa2 in functional lung development. Mol Cell Biol. 2011 Nov;31(21):4366-78
All:	1 reference(s)