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Gene Expression Data
Assay Details
Assay
Reference: J:39203 Varlet I, et al., nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development. 1997 Mar;124(5):1033-44
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5297906
Gene symbol: Nodal
Gene name: nodal growth differentiation factor
Reporter: lacZ
Direct Detection
Results
Specimen Not shown E3.5: embryonic day 3.5; Nodaltm1Rob/Nodal+ (more )
Note: Blastocyst.
Structure Level Pattern Image Note
TS4: blastocyst Absent

Specimen 1A: embryonic day 5.5; Nodaltm1Rob/Nodal+ (more )
Structure Level Pattern Image Note
TS8: epiblast Weak 1A
TS8: primitive endoderm Weak 1A
TS8: extraembryonic ectoderm Absent 1A

Specimen 1C: embryonic day 6.0; Nodaltm1Rob/Nodal+ (more )
Structure Level Pattern Image Note
TS8: epiblast Present 1C
TS8: extraembryonic ectoderm Present 1C
TS8: extraembryonic visceral endoderm Weak 1C

Specimen 1D: embryonic day 6.0; Nodaltm1Rob/Nodal+ (more )
Structure Level Pattern Image Note
TS8: epiblast Weak Regionally restricted 1D Expression is in the anterior epiblast.
TS8: extraembryonic visceral endoderm Weak 1D

Specimen 1E: embryonic day 6.0; Nodaltm1Rob/Nodal+ (more )
Structure Level Pattern Image Note
TS8: epiblast Weak Regionally restricted 1E Expression is in the anterior epiblast.
TS8: extraembryonic visceral endoderm Weak 1E

Specimen 1F: embryonic day 6.5; Nodaltm1Rob/Nodal+ (more )
Structure Level Pattern Image Note
TS9: embryo Present Regionally restricted 1F Expression is in the posterior embryo.

Specimen 1G: embryonic day 6.5; Nodaltm1Rob/Nodal+ (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Present 1G

Specimen 1H: embryonic day 6.5; Nodaltm1Rob/Nodal+ (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Strong Regionally restricted 1H Expression is high in the ectoderm adjacent to the streak, absent in anterior ectoderm.
TS9: embryo mesoderm Present Regionally restricted 1H Expression is in the nascent mesoderm emerging from the streak.
TS9: extraembryonic visceral endoderm Absent 1H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory