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Gene Expression Data
Assay Details
Assay
Reference: J:175832 Zhao F, et al., A heart-hand syndrome gene: Tfap2b plays a critical role in the development and remodeling of mouse ductus arteriosus and limb patterning. PLoS One. 2011;6(7):e22908
Assay type: RNA in situ
MGI Accession ID: MGI:5293662
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 probe32
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen E10.5 +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb Present 5_BMP4 10.5 +/+
Specimen E10.5 -/-: embryonic day 10.5; Tfap2btm1Rbu/Tfap2btm1Rbu (more )
Structure Level Pattern Image Note
TS17: limb Present 5_BMP4 10.5 -/- Expression increased in mutant limb bud compared with wild type embryos.
Specimen E11.5 +/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb Present 5_BMP4 11.5 +/+
Specimen E11.5 -/-: embryonic day 11.5; Tfap2btm1Rbu/Tfap2btm1Rbu (more )
Structure Level Pattern Image Note
TS19: limb Present 5_BMP4 11.5 -/- Expression increased in mutant limb bud compared with wild type embryos.
Specimen E12.5 +/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb Present 5_BMP4 12.5 +/+
Specimen E12.5 -/-: embryonic day 12.5; Tfap2btm1Rbu/Tfap2btm1Rbu (more )
Structure Level Pattern Image Note
TS20: limb Present 5_BMP4 12.5 -/- Expression increased in mutant limb bud compared with wild type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory